5-Amino-2-chloropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 56621-90-0 |
| Product name | 5-Amino-2-chloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Amino-2-chloropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Amino-2-chloropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Amino-2-chloropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing sulfonylurea herbicides (e.g., bensulfuron-methyl, pyrazosulfuron-ethyl) | Condensed with sulfonyl isocyanates or sulfonyl chlorides, followed by cyclization to produce the target herbicides |
| Pharmaceuticals | Used in synthesizing antiviral agents (e.g., ribavirin derivatives) and kinase inhibitor candidates | Employed in nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to introduce heterocyclic or aryl moieties |
| Dyes | Heterocyclic coupling component in azo and reactive dyes | Coupled with diazonium salts under mildly acidic conditions to construct pyrimidine-based azo chromophores |
Manufacturing Quality Control of 5-Amino-2-chloropyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical endpoint detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| pH of Aqueous Suspension | pH Meter Measurement | Measurement of pH in a defined saturated aqueous suspension (e.g., 10 mg/mL) using calibrated pH electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying sample at specified temperature (e.g., 105 C) for fixed duration under controlled atmosphere. |
| Residue on Ignition | Sulfated Ash Test | Mass of inorganic residue remaining after high-temperature incineration (700–800 C) following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed dry or wet sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution, indicating chiral purity and identity confirmation. |
Technical Specifications of 5-Amino-2-chloropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Amino-2-chloropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Amino-2-chloropyrimidine
Packaging of 5-Amino-2-chloropyrimidine
Industrial 5-Amino-2-chloropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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