China Factory Direct
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| CAS number | 56672-63-0 |
| Product name | Cbz-L-arginine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino acid protecting group in the synthesis of peptide-based drugs | Applied in peptide synthesis as the Cbz (benzyloxycarbonyl)-protected form of L-arginine to control reactivity and selectivity |
| Biopharmaceuticals | Synthesis of arginine derivatives and related bioactive molecules | Employed in the construction of arginine analogues with specific physiological activity via deprotection, coupling, and related steps |
| Organic Synthesis | Intermediate for synthesizing compounds containing the arginine moiety | Utilized in complex molecule assembly through selective deprotection or functional group transformation |
| Chemical Research | Studying the functional role of arginine in enzyme catalysis or protein–protein interactions | Used as a standard reagent in in vitro experiments to investigate the mechanistic role of arginine residues |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Cbz-L-arginine HCl content) | HPLC with UV detection | Quantification based on peak area comparison against certified reference standard using reversed-phase chromatography and UV absorbance at 220 nm. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer titration | Electrochemical titration measuring water via reaction of iodine with sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | Gas Chromatography (GC-FID) | Separation and quantification of volatile organic solvents (e.g., ethyl acetate, methanol) using flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion by plasma excitation and optical emission measurement. |
| Chloride Impurity | Potentiometric titration with silver nitrate | Titration based on formation of insoluble AgCl; endpoint detected by silver ion-selective electrode. |
| pH (1% aqueous solution) | pH meter measurement | Electrochemical measurement of hydrogen ion activity in a standardized aqueous solution at 25 C. |
| Related Substances | HPLC with gradient elution | Detection and quantification of structurally related impurities (e.g., Cbz-arginine, arginine HCl, de-Cbz product) using UV detection. |
| Loss on Drying | Gravimetric analysis (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile and moisture content. |
| Residue on Ignition | Sulfated ash gravimetry | Weight of inorganic residue after high-temperature combustion following sulfuric acid treatment. |
| Microbial Limits | Membrane filtration and plate count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
| Particle Size Distribution | Laser diffraction | Analysis of particle size distribution in dry powder form using light scattering principles. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192-196°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +12.0° to +14.0° (c=1, 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.