China Factory Direct
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| CAS number | 56751-12-3 |
| Product name | (R)-2-CHLORO-1-PHENYLETHANOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for manufacturing antidepressants (e.g., sertraline) and β-blockers | Optically pure (R)-isomer obtained via asymmetric reduction or enzymatic resolution, used in subsequent nucleophilic substitution or esterification reactions |
| Pesticides | Chiral pesticide intermediate for synthesizing stereoselective insecticides or fungicides | Prepared via epichlorohydrin ring-opening or acetophenone reduction-chlorination route, followed by chiral separation and purification |
| Chemical Reagents | Chiral building block for laboratory synthesis and asymmetric catalysis research | Used as a reference standard or chiral auxiliary in stereoselective reactions, such as Sharpless epoxidation or Noyori hydrogenation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID | Quantification by gas chromatography with flame ionization detection using a chiral or non-chiral column and external standard calibration. |
| Enantiomeric Excess (ee) | Chiral GC or Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, followed by peak area comparison to calculate enantiomeric excess. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a controlled anhydrous medium. |
| Residual Solvents | GC-FID with Headspace | Detection and quantification of volatile organic solvents (e.g., methanol, acetone, ethyl acetate) using headspace sampling and GC-FID. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, based on atomic emission intensity at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using an anion-exchange column and conductivity detection. |
| Acidity (as HCl) | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Color | Visual Comparison or Spectrophotometry (APHA) | Assessment of yellowness/brownness by visual match to APHA color standards or measurement of absorbance at 430 nm in solution. |
| Density | Digital Density Meter | Measurement of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Determination of refractive index at 20 degrees C using a calibrated Abbe refractometer based on critical angle of total internal reflection. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing of sample in a platinum crucible. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., 1-phenylethanol, benzaldehyde, chlorinated by-products) using reversed-phase HPLC with UV detection at 210–254 nm. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Optical Rotation | -12.0° to -14.0° (c=1, in chloroform) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.542 to 1.546 |
| Relative Density (20°C/25°C) | 1.135 to 1.145 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.