China Factory Direct
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| CAS number | 5678-45-5 |
| Product name | 3-Amino-3-(4-methoxyphenyl)propionic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antihypertensive drug telmisartan | Produced via asymmetric hydrogenation or enzymatic reduction of 3-oxo-3-(4-methoxyphenyl)propanoic acid derivatives, followed by amination or transamination to install the C3 amino group; alternatively employed as a chiral building block in multistep coupling and cyclization reactions to construct the benzimidazole core of telmisartan |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; reported as area percent relative to total chromatogram. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine water based on stoichiometric reaction with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue as sulfate ash. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with conductivity detection; chloride quantified via calibration curve. |
| Sulfate Impurity | Ion Chromatography | Same principle as chloride, using specific eluent and conductivity detection for sulfate quantification. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution to determine enantiomeric purity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary tube method per USP <741>. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a 1% w/v aqueous solution at 25 C. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C for 2 hours under vacuum or air flow. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references in controlled lighting conditions. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.