China Factory Direct
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| CAS number | 5680-86-4 |
| Product name | (S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-benzyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of peptide-based drugs and protected amino acid derivatives, including anticancer agents and antimicrobial peptides | Acts as a dual protecting group for the glutamic acid side-chain carboxyl and α-amino groups in solid-phase peptide synthesis (SPPS); the α-amino group is protected with Cbz (benzyloxycarbonyl) and the γ-carboxyl group with a benzyl ester; the 5-position benzyl ester can be selectively removed during subsequent deprotection steps |
| Organic Synthesis | Serves as a chiral building block in asymmetric synthesis for preparing cyclic peptides, enzyme inhibitors, and targeted molecular probes | Enables stepwise deprotection via selective removal of the benzyloxycarbonyl and/or benzyl ester groups under palladium-catalyzed hydrogenation or trifluoroacetic acid/hydrochloric acid conditions—suitable for assembling complex peptide sequences |
| Biochemical Research | Employed as a precursor for site-specific protein modification and fluorescent labeling in structural and functional studies | Coupled to fluorescent dyes (e.g., FITC) or biotin via activated carboxyl groups, followed by mild hydrogenolytic debenzylization to introduce functional tags |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by HPLC separation and UV absorbance relative to the main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, toluene) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-OES | Quantifies elements such as Pb, Cd, Hg, and As after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion in presence of sulfuric acid, followed by weighing. |
| Optical Rotation | [alpha]D Measurement | Determines specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using calibrated capillary method per USP <741>. |
| Residual Palladium | ICP-MS | Quantifies trace palladium from catalytic hydrogenation steps using inductively coupled plasma mass spectrometry. |
| pH of Solution | Potentiometric pH Measurement | Determines acidity/basicity of a standardized aqueous suspension using a calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size via light scattering pattern generated by dispersed sample in air. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | -7.0 to -10.0° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.