2,4-Dichloro-5-methylpyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 56961-78-5 |
| Product name | 2,4-Dichloro-5-methylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Dichloro-5-methylpyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Dichloro-5-methylpyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Dichloro-5-methylpyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the fungicide fluazinam | Used to construct the fluazinam molecular scaffold via nucleophilic substitution with compounds such as 2-amino-3-chloro-5-(trifluoromethyl)pyridine |
| Pesticides | Synthetic intermediate for the insecticide chlorfenapyr | Applied in constructing pyridine ring substituents of the target molecule through multi-step reactions including nitration, reduction, diazotization, and coupling |
| Pharmaceuticals | Structural modification unit in antitumor drug candidates | Employed as a chloropyridyl pharmacophore to introduce hydrophobicity and modulate electronic effects in medicinal chemistry |
| Materials Science | Building block for electron-transport materials in organic light-emitting diode (OLED) devices | Incorporated into conjugated backbones via Suzuki or Ullmann coupling to enhance electron affinity and thermal stability |
Manufacturing Quality Control of 2,4-Dichloro-5-methylpyridine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase chromatography column, with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (usually at 254 nm) for detection. Quantification is performed using external standard or internal standard methods, offering high resolution and accuracy, suitable for determination of the main component content. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC) | Same method as content determination, but with optimized gradient elution to separate structurally similar impurities (e.g., mono-chlorinated derivatives, demethylated products, oxidation products, etc.). Quantification is performed by peak area normalization or comparison with impurity reference standards. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction between iodine, sulfur dioxide, pyridine, and methanol with water, using potentiometric or coulometric methods to determine trace moisture in organic solvents. Applicable for precise determination of trace water content (standard: GB/T 6283 or ISO 760). |
| Melting Point | Melting Point Apparatus Method | Determine the melting range using a digital melting point apparatus, serving as an initial criterion for purity assessment. The typical melting point of 2,4-dichloro-5-methylpyridine is 58–61°C; deviation from this range indicates the presence of impurities. |
| Chlorine Content | Oxygen Bomb Combustion - Ion Chromatography (or Microcoulometry) | The sample is combusted in an oxygen bomb to convert chlorine into chloride ions, which are then measured using ion chromatography (IC), or determined via microcoulometry through electrolytic titration. This method is used to verify whether the theoretical chlorine content in the molecule meets the required specifications. |
| Residual Solvent Analysis | Gas Chromatography (GC) | Use headspace or direct injection GC-FID according to ICH Q3C guidelines to detect residual organic solvents such as ethanol, acetone, toluene, dichloromethane, etc. Quantification is performed using an internal standard method to ensure compliance with pharmaceutical or food-grade standards. |
| Appearance and Color | Visual Inspection + Colorimetry | Observe the solid color (should be white to pale yellow crystals). When necessary, use a colorimeter or colorimetric methods (e.g., APHA or Pt-Co scale) to quantitatively assess the color intensity, reflecting the degree of purification. |
| Particle Size Distribution (if applicable) | Laser Diffraction | Used for powder morphology control, measuring particle size distribution to ensure good flowability and solubility in formulation or reactions. Applicable for standardization of industrial-grade products. |
| UV-Visible Absorption Spectroscopy | UV-Visible Spectrophotometry | Measure absorbance at specific wavelengths (e.g., 254 nm) for rapid identification and preliminary purity evaluation. Often used as a supplementary method to HPLC and requires calibration with standard samples. |
| Nitrogen Content Determination (Elemental Analysis) | Elemental Analyzer (CHNS/O) | Determine the content of C, H, N, S, and O elements after high-temperature combustion of the sample. Compare with theoretical values to verify molecular composition. Suitable for confirming the composition of high-purity reference materials. |
Technical Specifications of 2,4-Dichloro-5-methylpyridine
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 36–38°C |
| Refractive Index (n20/D) | 1.538–1.542 |
| Relative Density (20°C/25°C) | 1.275–1.285 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Dichloro-5-methylpyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Dichloro-5-methylpyridine
Safety Information of 2,4-Dichloro-5-methylpyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-Dichloro-5-methylpyridine
Industrial 2,4-Dichloro-5-methylpyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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