4-MALEIMIDOBUTYRIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 57078-98-5 |
| Product name | 4-MALEIMIDOBUTYRIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-MALEIMIDOBUTYRIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-MALEIMIDOBUTYRIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-MALEIMIDOBUTYRIC ACID
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Site-specific modification of proteins/peptides for antibody–drug conjugate (ADC) construction | Selective covalent conjugation to cysteine residues via Michael addition of maleimide to thiol (–SH) groups in a pH 6.5–7.5 buffer system |
| Life Science Research | Site-specific conjugation of functional molecules (e.g., fluorescent probes, biotin) to proteins | Reaction for 1–2 hours at room temperature in PBS or HEPES buffer, followed by removal of unreacted reagents via gel filtration or dialysis |
| Materials Science | Crosslinker for functional hydrogels and biocompatible polymers | Participates as a bifunctional crosslinker in thiol–ene click reactions, copolymerizing with thiol-containing polymers (e.g., PEG-SH) to form degradable networks |
Manufacturing Quality Control of 4-MALEIMIDOBUTYRIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by reverse-phase HPLC with UV detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, ethyl acetate) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized sodium hydroxide solution using phenolphthalein indicator; measures free carboxylic acid groups. |
| Maleimide Content | UV-Vis Spectrophotometry | Quantification of maleimide group absorbance at ~250-260 nm using molar absorptivity and Beer-Lambert law. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; quantifies Pb, Cd, Hg, As, and other regulated metals by atomic emission intensity. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to combust organic matter; residue weight measured as inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary method per USP/EP guidelines. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 589 nm to assess chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie theory to determine volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms via filtration, membrane transfer to culture media, and colony counting after incubation. |
Technical Specifications of 4-MALEIMIDOBUTYRIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | ≥99.0% |
| Melting point | 92.0~99.0℃ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-MALEIMIDOBUTYRIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-MALEIMIDOBUTYRIC ACID
Packaging of 4-MALEIMIDOBUTYRIC ACID
Industrial 4-MALEIMIDOBUTYRIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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