China Factory Direct
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| CAS number | 5708-19-0 |
| Product name | (S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for anti-inflammatory drugs, neurotransmitter modulators, and other pharmaceuticals | (S)-(−)-3-Cyclohexene carboxylic acid is produced via asymmetric synthesis or chiral resolution and used in subsequent esterification, amidation, or coupling reactions to construct drug molecule scaffolds |
| Pesticides | Synthesis of biologically active cyclohexene-based insecticides or plant growth regulators | Used as a chiral building block in functional group transformations of cyclohexene derivatives to generate stereoselective active ingredients |
| Chemical Reagents | Chiral catalysis research and asymmetric reaction templates in laboratory settings | Employed as a chiral ligand or auxiliary in transition metal-catalyzed asymmetric addition, hydrogenation, or cyclization reactions |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Form | Visual Inspection + Physical Property Determination | Observe sample color and state (typically a colorless to pale yellow liquid or low-melting solid), and determine melting or boiling point range, conforming to pharmacopoeial or enterprise standards. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with water-acetonitrile or methanol as mobile phase, and a UV detector (210–254 nm) to quantify the main component via external or internal standard method. Purity typically required to be ≥98.0%. |
| Enantiomeric Purity (ee Value) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employ chiral stationary phase columns (e.g., Chiralpak AD-H, OD-H, or similar) to separate (S)- and (R)-enantiomers. Enantiomeric excess (ee) is calculated from peak areas, typically requiring ≥99% ee. |
| Moisture Content | Karl Fischer Titration | Quantify trace water content using the reaction of iodine, sulfur dioxide, pyridine, and methanol. Suitable for organic acid compounds, with moisture controlled ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection, with a capillary column (e.g., DB-624) and FID detector, to detect residual solvents such as ethanol, acetone, ethyl acetate, etc., in compliance with ICH Q3C guidelines. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic, meeting pharmacopoeial limits (e.g., Pb ≤5 ppm). |
| Acid Value (Total Acid Content) | Alkaline Titration | Titrate the sample with standard sodium hydroxide solution using phenolphthalein as indicator. Acid value (mg KOH/g) is calculated to verify carboxyl group content against theoretical value. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Measure maximum absorption wavelength (λmax, typically around 210–220 nm) within the 200–300 nm range, used for preliminary identification and purity screening. |
| Melting Point / Boiling Point | Melting Point Apparatus / Boiling Point Determination | Determine physical constants; (S)-(-)-3-Cyclohexenecarboxylic acid has a melting point of approximately 20–25°C (liquid) and boiling point of about 180–190°C (at atmospheric pressure), used for auxiliary identification. |
| Impurities (e.g., Chlorides, Sulfates) | Ion Chromatography (IC) or Colorimetric Methods | Use ion chromatography to detect anionic impurities (Cl⁻, SO₄²⁻), or classical colorimetric methods (e.g., silver chloride precipitation) to control inorganic impurity levels. |
| Microbial Limits (if applicable) | Microbial Limit Test (Pharmacopoeial Method) | If used as a pharmaceutical intermediate or active pharmaceutical ingredient, test for total aerobic microbial count, molds and yeasts, and specified pathogens (e.g., Escherichia coli), meeting USP/EP microbial limits. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC) |
| Optical Rotation | -97.0 to -92.0 deg (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 185.0 to 195.0 mg KOH/g |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.