China Factory Direct
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| CAS number | 571189-16-7 |
| Product name | 1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediate for synthesizing targeted kinase inhibitors (e.g., JAK2 inhibitors) | Condensation with acyl chlorides or sulfonyl chlorides in inert solvents (e.g., THF or DCM); or palladium-catalyzed cross-coupling with aryl halides following deprotection |
| Agrochemical R&D | Structural motif for novel insecticides/acaricides, used to construct bioactive molecules containing pyridine-piperazine heterocycles | Key intermediate in multistep synthesis—e.g., reductive amination with specific aldehydes or reaction with isocyanates to form urea derivatives |
| Materials Science | Precursor for organic functional materials, used to prepare conjugated small molecules with electron-transport properties | Introduction of conjugated side chains via Suzuki or Heck coupling, followed by acid-mediated Boc deprotection to enable subsequent polymerization or film-forming processes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma ionization. |
| Chloride Content | Ion Chromatography | Separation and conductivity-based quantification of chloride ions in solution. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue via atomic emission from inductively coupled plasma. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light to assess chiral purity and enantiomeric identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection by visual observation of solid-to-liquid phase change under controlled heating. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate size distribution of solid particles in suspension. |
| Loss on Drying | Gravimetric Thermogravimetry | Mass loss measurement after controlled heating to remove volatile components. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Hydrogen ion activity determination using calibrated glass electrode in a saturated aqueous slurry. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.