China Factory Direct
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| CAS number | 571189-49-6 |
| Product name | 1-METHYL-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antipsychotics, antidepressants, and other central nervous system-active compounds | Serves as a key intermediate in organic synthesis, enabling construction of complex molecular frameworks via Suzuki coupling, Buchwald–Hartwig amination, and related reactions |
| Pesticides | Potential pesticide intermediate for developing novel insecticides or herbicides (research stage) | Structural modification to incorporate pyridine and piperazine moieties, optimizing biological activity and selectivity |
| Research | Used as a lead compound or probe molecule in medicinal chemistry and chemical biology research | Multi-step organic synthesis for structure–activity relationship (SAR) studies and target validation |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Structural Elucidation | Proton Nuclear Magnetic Resonance (¹H NMR) | Confirms the chemical environment and number of hydrogen atoms through chemical shifts, coupling constants, and integration areas, thereby verifying the target molecular structure. |
| Carbon-13 Nuclear Magnetic Resonance (¹³C NMR) | Confirms the carbon skeleton structure and assists in determining substitution positions and functional group connectivity. | |
| Mass Spectrometry (MS, e.g., ESI-MS or HRMS) | Determines molecular ion peaks to confirm molecular weight; high-resolution mass spectrometry enables precise elemental composition matching for definitive molecular formula confirmation. | |
| Infrared Spectroscopy (IR) | Identifies characteristic functional group absorption bands (e.g., N-H stretch, C=N, C-N), aiding in structural verification. | |
| Content Determination | High-Performance Liquid Chromatography with UV Detection (HPLC-UV) | Uses reversed-phase chromatography columns and UV detection (e.g., 254 nm or set at maximum absorption wavelength); quantifies the main component using external standard or internal standard method. |
| Related Substances / Impurity Profiling | HPLC-UV (Gradient Elution) | Optimizes gradient mobile phase for effective separation of potential process impurities and degradation products; evaluates impurity profile based on relative retention times and peak purity. |
| Chiral Purity (if applicable) | Chiral HPLC or Capillary Electrophoresis | If chiral centers exist, enantiomers are separated using chiral columns or chiral additives to control optical purity. |
| Moisture Content | Karl Fischer Titration | Measures water content via potentiometric or volumetric titration, ensuring compliance with loss-on-drying or specific limit requirements. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Uses headspace or direct injection to detect residual organic solvents (e.g., methanol, acetonitrile, dichloromethane) from synthesis or purification processes. |
| Heavy Metals / Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Per ICH Q3D guidelines, detects harmful element residues such as lead, cadmium, arsenic, and mercury to ensure compliance with safety limits. |
| pH / Acidity-alkalinity | pH Meter Measurement (in aqueous or buffer solution) | Sample is dissolved at a defined concentration and pH is measured, reflecting its acidity/basicity which affects stability and formulation compatibility. |
| Melting Point Determination | Capillary Melting Point Apparatus | Measures the melting range of solid samples as a physical constant used for preliminary identification and purity assessment (pure compounds typically exhibit narrow melting ranges). |
| Specific Rotation (if chiral) | Polarimeter | For chiral compounds, specific rotation is measured to characterize optical activity and ensure batch-to-batch consistency. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 148°C - 152°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.