5-Bromo-3-nitropyridine-2-carbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 573675-25-9 |
| Product name | 5-Bromo-3-nitropyridine-2-carbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-3-nitropyridine-2-carbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-3-nitropyridine-2-carbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-3-nitropyridine-2-carbonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used as an intermediate in the synthesis of multiple pharmaceuticals, participating in the construction of specific compounds. |
| Agrochemicals | Raw material | Applied in the synthesis of agrochemical products containing insecticidal, fungicidal, and other biologically active ingredients. |
| Fine chemicals | Synthetic reagent | Employed as a key reactant or catalyst in organic synthesis to facilitate specific chemical reactions. |
Manufacturing Quality Control of 5-Bromo-3-nitropyridine-2-carbonitrile
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Properties | Visual Inspection + Microscopic Observation | Observe sample color, crystalline morphology, presence of impurity particles or foreign substances. Typically appears as yellow to orange-red crystalline powder. |
| Melting Point | Capillary Melting Point Apparatus Method | Determine the melting temperature range using a melting point apparatus and compare it with standard values (literature value ~120–125°C) to assess purity. |
| Content (Main Component Purity) | High-Performance Liquid Chromatography (HPLC) | Use a C18 reverse-phase chromatographic column with methanol/water or acetonitrile/water gradient elution. Quantify using a UV detector (254–280 nm), and calculate main component content via external standard method. |
| Organic Impurities (Related Substances) | HPLC or UPLC (Gradient Elution) | Use more sensitive UPLC or HPLC gradient programs to detect possible unreacted raw materials, by-products (e.g., dinitro compounds, debrominated products), and degradation products. Quantify using normalized peak area method or impurity reference standard method. |
| Bromine Content | Ion Chromatography (IC) or ICP-MS | After alkali fusion or acid digestion of the sample, detect bromide ions using ion chromatography, or directly determine total bromine content using inductively coupled plasma mass spectrometry (ICP-MS) to ensure compliance with chemical formula requirements. |
| Nitro Group Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm the presence of nitro groups through characteristic absorption peaks (e.g., ~1520 cm⁻¹ and ~1340 cm⁻¹ for asymmetric and symmetric stretching vibrations of nitro groups), comparing with standard spectra. |
| Cyano Group Confirmation | FT-IR or Proton Nuclear Magnetic Resonance (¹H NMR) | In FT-IR, the cyano group shows a characteristic peak at ~2240 cm⁻¹; in ¹H NMR, proton shifts of pyridine ring protons (δ 8.5–9.0 ppm) match the substitution pattern to verify structural integrity. |
| Solvent Residue | Gas Chromatography (GC-FID/MS) | Detect residual solvents (e.g., DMF, acetonitrile, methanol) according to ICH Q3C guidelines. Use headspace sampling or direct injection with FID or MS detection to ensure compliance with pharmacopoeial limits. |
| Moisture Content | Karl Fischer Titration | Determine trace moisture content using coulometric or volumetric Karl Fischer titration to control moisture within ≤0.5%, preventing hydrolysis or storage stability issues. |
| Heavy Metal Impurities | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After wet digestion of the sample, determine heavy metal content such as lead, cadmium, mercury, and arsenic to meet ICH Q3D or pharmacopoeial limits (e.g., ≤10 ppm). |
| Particle Size Distribution (if applicable) | Laser Diffraction Particle Size Analyzer | For APIs requiring controlled flowability or formulation process, measure particle size distribution to ensure consistency between batches. |
Technical Specifications of 5-Bromo-3-nitropyridine-2-carbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Light orange to yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-3-nitropyridine-2-carbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-3-nitropyridine-2-carbonitrile
Safety Information of 5-Bromo-3-nitropyridine-2-carbonitrile
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Bromo-3-nitropyridine-2-carbonitrile
Industrial 5-Bromo-3-nitropyridine-2-carbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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