2-Bromo-5-fluorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 57381-39-2 |
| Product name | 2-Bromo-5-fluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Bromo-5-fluorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Bromo-5-fluorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Bromo-5-fluorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer agents such as Vismodegib (GDC-0449) | Used to construct the drug molecule backbone via coupling and substitution reactions |
| Agrochemicals | Intermediate in the synthesis of fluorinated or brominated insecticides or herbicides | Applied to build heterocyclic or aromatic structures with specific biological activity |
| Liquid Crystal Materials | Used in the synthesis of high-performance liquid crystal monomers or intermediates | Leverages its unique fluorine-bromine substituted structure to modulate the physicochemical properties of liquid crystal molecules |
Manufacturing Quality Control of 2-Bromo-5-fluorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and gradient elution with UV detection at 220 nm. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling and FID | Headspace GC analysis to quantify volatile organic solvents (e.g., dichloromethane, acetone) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantification after acid digestion; detection based on element-specific atomic emission lines. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on anion-exchange column followed by quantitative detection via suppressed conductivity. |
| Residue on Ignition | Gravimetric analysis after high-temperature ashing | Mass of non-volatile residue determined after incineration at 700-800 C in a muffle furnace. |
| Melting Point | Capillary melting point apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs under controlled heating. |
| Appearance | Visual inspection against white/black background | Assessment of physical state, color, and presence of visible particles or discoloration in a glass vial under controlled lighting. |
| pH of Aqueous Suspension | pH meter measurement | Determination of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution of known concentration and path length. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Size distribution derived from angular dependence of laser light scattering by dispersed particles in liquid medium. |
Technical Specifications of 2-Bromo-5-fluorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 72.0–76.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Bromo-5-fluorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Bromo-5-fluorobenzonitrile
Packaging of 2-Bromo-5-fluorobenzonitrile
Industrial 2-Bromo-5-fluorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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