4-Chloro-2-fluorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 57381-51-8 |
| Product name | 4-Chloro-2-fluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-2-fluorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-2-fluorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-2-fluorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of synthetic pyrethroid insecticides (e.g., cyfluthrin, beta-cyfluthrin) | Constructs the chrysanthemic acid side chain or aryl structure via organic synthesis steps including nucleophilic substitution and coupling reactions |
| Pharmaceuticals | Used to synthesize fluorinated aromatic heterocyclic drug molecules, such as precursors for antidepressants and anticancer agents | Introduces active functional groups or constructs the heterocyclic scaffold via nitrile hydrolysis, reduction, or cyclization reactions |
| Dyes & Pigments | Synthesis intermediate for high-performance organic pigments or fluorescent dyes | Participates in dye synthesis processes including diazotization, coupling, or metal complexation |
| Electronic Chemicals | Used to prepare liquid crystal monomers or organic optoelectronic materials | Builds conjugated aromatic systems via Suzuki coupling, Ullmann reaction, and related methods |
Manufacturing Quality Control of 4-Chloro-2-fluorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic impurities are vaporized in sealed vials and quantified by GC-FID or GC-MS relative to internal standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using anion-exchange column and conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element detection after acid digestion, based on mass-to-charge ratio and isotopic abundance. |
| Residual Catalyst (Pd) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantification of palladium via characteristic atomic emission lines after microwave-assisted acid digestion. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation on reversed-phase C18 column; impurities detected at 220 nm and quantified by external standard method. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature at which solid phase converts to liquid. |
| Appearance | Visual Inspection | Assessment of physical state and color under controlled white light against standard reference for clarity and absence of particulates. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Loss on Drying (LOD) | Gravimetric Analysis (Thermogravimetric) | Mass loss measured after drying at specified temperature (e.g., 105 C) until constant weight is achieved. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or enantiomeric excess in solution. |
Technical Specifications of 4-Chloro-2-fluorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 65–69°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-2-fluorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-2-fluorobenzonitrile
Packaging of 4-Chloro-2-fluorobenzonitrile
Industrial 4-Chloro-2-fluorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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