China Factory Direct
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| CAS number | 5751-20-2 |
| Product name | 2-Methylthio-4-pyrimidinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a pharmaceutical intermediate | Applied in the synthesis of pyrimidine-based drugs |
| Agrochemicals | As an agrochemical intermediate | Applied in the synthesis of fungicides and insecticides |
| Fine chemicals | As a raw material for fine chemicals | Applied in the synthesis of other pyrimidinone compounds |
| Dyes | As a dye intermediate | Applied in the synthesis of azo dyes |
| Food additives | As a food additive intermediate | Applied in the synthesis of antioxidants |
| Personal care | As a cosmetic intermediate | Applied in the synthesis of UV absorbers |
| Process considerations: | ||
| – Synthesis | Introduction of the methylthio group | Substitution reaction using methanethiol or other methylthio donors |
| – Oxidation | Synthesis of imidazolinone | Oxidation to form the pyrimidinone structure |
| – Separation | Purification | Purification via recrystallization or column chromatography |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities under natural light or standard illumination. |
| Purity and Active Ingredient Content | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase column (e.g., C18) with a UV detector (typically at 260–280 nm wavelength); qualitative identification is based on retention time, and quantitative analysis is performed via external standard calibration using peak area. Effectively separates impurities and accurately determines target compound content. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Perform structural analysis using ¹H-NMR and ¹³C-NMR to assign hydrogen and carbon signals corresponding to the methylthio group and pyrimidine ring, verifying the molecular structure. |
| Structure Confirmation | Mass Spectrometry (MS) | Employ electrospray ionization (ESI) or electron ionization (EI) mass spectrometry to determine molecular ion peaks ([M+H]+ or M•+) and analyze fragment ion patterns for molecular weight confirmation. |
| Water Content | Karl Fischer Titration | Utilize the quantitative reaction of iodine and sulfur dioxide in the presence of pyridine and methanol with water; measure water content via coulometric titration, suitable for trace moisture analysis. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, use a capillary column and FID detector to identify and quantify residual organic solvents (e.g., methanol, ethanol, acetone) potentially present from manufacturing processes. |
| Melting Point | Melting Point Determination (Capillary Method) | Load the sample into a capillary tube and gradually heat it in a melting point apparatus; observe the initial and complete melting temperatures for identification and preliminary purity assessment. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure residual levels of heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopeial or safety limits. |
| Related Substances (Impurities) | HPLC-UV or LC-MS | Separate degradation products or synthetic by-products using gradient elution; identify and quantify individual impurities using UV or mass spectrometry detectors to evaluate sample stability and process purity. |
| Particle Size Distribution (if solid) | Laser Diffraction Particle Size Analysis | Disperse the sample in a liquid or gas medium and determine particle size distribution based on laser diffraction principles; applicable for pre-formulation studies. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 215-219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.