D-4-Hydroxyphenylglycine Methyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 57591-61-4 |
| Product name | D-4-Hydroxyphenylglycine Methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for D-4-Hydroxyphenylglycine Methyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-4-Hydroxyphenylglycine Methyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key side-chain raw material for synthesizing β-lactam antibiotics (e.g., amoxicillin, cephalexin) | Used as a pharmaceutical intermediate in chiral resolution or asymmetric synthesis to construct antibiotic molecular frameworks |
| Pharmaceuticals | Synthesis of oral cephalosporin antibiotics | Serves as a D-hydroxyphenylglycine derivative in condensation reactions during semi-synthetic cephalosporin production |
| Organic Synthesis | Research on chiral compound synthesis and resolution | Employed as a chiral building block or intermediate in the development of fine chemical synthesis routes |
Manufacturing Quality Control of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural or standard lighting conditions. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus to assess purity and identify substance characteristics. |
| Specific Optical Rotation | Polarimetry | Measure specific optical rotation using a polarimeter at a specified wavelength (e.g., sodium D line, 589 nm) and temperature to confirm D-configuration and purity. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with UV detection (typically 220–280 nm) and external or internal standard method for quantitative analysis of the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak from impurity peaks using gradient or isocratic elution; calculate individual and total impurity levels to evaluate purity. |
| Water Content | Karl Fischer Titration | Accurately determine water content using Karl Fischer titration, suitable for quality control of moisture-sensitive compounds. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, dichloromethane) in accordance with ICH guidelines. |
| Chlorides (Hydrochloride Form) | Ion Chromatography or Argentometric Titration | Ion chromatography provides accurate quantification of chloride ions; argentometric titration uses silver nitrate titration to determine chloride content and verify hydrochloride stoichiometry. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with safety limits for pharmaceutical excipients or active pharmaceutical ingredients (e.g., ≤10–20 ppm). |
| Sulfated Ash / Residue on Ignition | Gravimetric Method (Residue on Ignition Test) | Weigh the residue remaining after high-temperature ignition of the sample to estimate total inorganic impurities. |
| pH (Solution) | pH Meter Method | Dissolve the sample in water (e.g., 1% w/v), then measure acidity or alkalinity using a calibrated pH meter. |
| Microbial Limits | Microbial Limits Test (Pharmacopoeial Method) | Perform tests for total aerobic microbial count, total combined molds and yeasts count, and specified microorganisms (e.g., Escherichia coli) according to requirements of the Chinese Pharmacopoeia or USP. |
Technical Specifications of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | -125.0 to -115.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
Safety Information of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-4-Hydroxyphenylglycine Methyl ester hydrochloride
Industrial D-4-Hydroxyphenylglycine Methyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply