CIS-ZHPROME Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 57653-35-7 |
| Product name | CIS-ZHPROME |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for CIS-ZHPROME
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk CIS-ZHPROME Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of CIS-ZHPROME
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antiviral drug intermediates | Used as a chiral building block to construct complex molecular frameworks in multistep organic synthesis |
| Pharmaceutical R&D | Synthesis precursor for protease inhibitors | Introduces modified proline residues in solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Construction of peptide mimetics | Prepares hydroxyproline derivatives with defined stereochemistry via ester hydrolysis and deprotection |
| Pharmaceutical Manufacturing | Synthesis of anticancer drug candidates | Serves as a key intermediate in constructing cyclic peptides containing hydroxyproline |
Manufacturing Quality Control of CIS-ZHPROME
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase C18 column and gradient elution. |
| Chiral Purity | Chiral HPLC | Resolves enantiomers using chiral stationary phase; measures % of desired cis-L-isomer relative to total stereoisomers. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., N-CBZ-trans-L-hydroxyproline methyl ester, deprotected hydroxyproline) via retention time comparison. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., methanol, ethyl acetate, toluene) using capillary column and flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of palladium from catalytic hydrogenation steps using high-sensitivity mass detection after sample digestion. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid content by titration with standardized NaOH solution using phenolphthalein indicator. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line light to confirm chiral integrity and concentration-dependent optical activity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition to verify identity and crystallinity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular variation in laser light scattering intensity. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample through membrane, culturing on agar, and counting colony-forming units. |
Technical Specifications of CIS-ZHPROME
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | +15.0 to +19.0° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of CIS-ZHPROME
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of CIS-ZHPROME
Packaging of CIS-ZHPROME
Industrial CIS-ZHPROME Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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