China Factory Direct
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| CAS number | 57999-06-1 |
| Product name | 4-PHENYL-1H-PYRAZOL-5-AMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthetic intermediate for pharmaceuticals | Serves as a key building block in coupling or cyclization reactions to synthesize pyrazole-containing drug molecules. |
| Pharmaceutical Chemicals | Kinase inhibitor development | Used in constructing small-molecule inhibitors targeting specific kinases (e.g., CDK, JAK), leveraging its amino group and pyrazole core structure. |
| Chemical Reagents | Bio-probe synthesis | Acts as an active reaction site in the synthesis of functional dyes or biomarker molecules. |
| Organic Synthesis | Heterocyclic compound construction | Undergoes acylation or alkylation via nucleophilic amino group, or serves as a pyrazole scaffold for constructing more complex fused-ring systems. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separates and quantifies impurities by HPLC-UV using gradient elution and relative response factors or external standards. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., ethanol, acetone) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine/methanol-based reagent. |
| Heavy Metals | ICP-OES | Measures total elemental metal content (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion of sample with sulfuric acid followed by high-temperature ashing and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined reference standards. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension (1% w/v) using calibrated pH electrode per EP 2.2.3. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile matter loss by measuring mass change upon heating at 105 C for 2 hours under controlled airflow. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder using Mie scattering theory applied to laser light diffraction patterns. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 152-156°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.