ADP Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 58-64-0 |
| Product name | ADP |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ADP
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ADP Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ADP
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | As an intermediate in cellular energy metabolism, used to study ATP synthesis and energy transfer mechanisms | Enzymatic reactions, cell culture, metabolic pathway analysis |
| Clinical Diagnostics | For platelet aggregation function testing (e.g., ADP-induced platelet aggregation assay) | In vitro diagnostic reagent formulation, blood sample processing |
| Molecular Biology | As a substrate or cofactor in RNA synthesis and modification reactions | In vitro transcription, kinase/phosphatase activity assays |
| Pharmaceutical R&D | As a P2Y receptor agonist for cardiovascular and antithrombotic drug screening | High-throughput screening, receptor binding assays |
| Food Science | As a flavor enhancer precursor (generated during specific fermentation processes) | Microbial fermentation, food additive research (research use only) |
Manufacturing Quality Control of ADP
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column, with phosphate buffer-methanol or acetonitrile as the mobile phase, and UV detection at 254 nm. The area of the ADP peak is measured, and the content is calculated by external standard method. It offers high accuracy and is suitable for purity and quantitative analysis. |
| Liquid Chromatography-Mass Spectrometry (LC-MS/MS) | Utilizes the high selectivity and sensitivity of mass spectrometry to quantify ADP using multiple reaction monitoring (MRM) mode. It is suitable for accurate determination of trace ADP in complex matrices, often used for biological samples or verification of high-purity standards. | |
| Purity and Impurity Analysis | Ion Chromatography (IC) | Used for detecting inorganic anion impurities in ADP (such as phosphates and sulfates). The separation is performed on an anion-exchange column, with conductivity detection for quantification. It complies with pharmacopoeia requirements for inorganic impurity control. |
| Capillary Electrophoresis (CE) | Separates ADP based on differences in migration rate under electric field, combined with UV or laser-induced fluorescence detection. It offers high resolution and is suitable for analyzing structurally similar impurities (e.g., AMP, ATP). | |
| Moisture Content Determination | Karl Fischer Titration | Quantitatively reacts with water through the iodine-sulfur dioxide-pyridine-methanol system to determine the residual moisture content in ADP. It complies with the Chinese Pharmacopoeia General Chapter 0832, suitable for moisture control in solid raw materials. |
| pH Value Determination | Glass Electrode Method | ADP solution is prepared at a specified concentration (e.g., 10 mg/mL), and pH is measured using a pH meter to ensure compliance with the acid-base range specified in the pharmacopoeia (typically pH 5.0–7.0), reflecting formulation stability. |
| Solution Clarity and Color | Visual Inspection or Spectrophotometry | Prepared according to pharmacopoeia specifications, clarity is visually checked; or absorbance is measured using a UV-Vis spectrophotometer in the 450–700 nm wavelength range to control the introduction of colored impurities (e.g., degradation products). |
| Heavy Metal Testing | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After ashing or digestion, heavy metal content (e.g., lead, cadmium, mercury) is determined by AAS, or multi-element simultaneous detection is achieved by ICP-MS, complying with the Heavy Metals Testing General Chapter of the Chinese Pharmacopoeia. |
| Microbial Limit | Plate Count Method / MPN Method | Tests total aerobic bacteria, mold and yeast counts, and control bacteria (e.g., Escherichia coli) according to General Chapters 1105/1106 of the Chinese Pharmacopoeia, applicable for biocompatibility control of non-sterile raw materials. |
| Pyrogen or Bacterial Endotoxin | Limulus Amebocyte Lysate (LAL) Method | Uses limulus reagent to induce coagulation with endotoxins, and detects bacterial endotoxin content via gel, turbidity, or colorimetric methods. It ensures that injectable ADP is free from pyrogen contamination (limit usually ≤0.25 EU/mg). |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Confirms the molecular structure of ADP by characteristic proton and carbon signals (e.g., adenine ring protons, ribose hydrogens, phosphate group signals), used for identification and structural integrity verification of raw materials. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Compares the infrared absorption spectrum of the sample with that of the reference standard to confirm consistent functional group (e.g., phosphate ester bond, adenine ring) characteristic peaks, used for qualitative identification. |
Technical Specifications of ADP
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -26.0 to -25.0 deg (c=1, H2O) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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NMR Spectra of ADP
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Industrial ADP Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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