D-Biotin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 58-85-5 |
| Product name | D-Biotin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Biotin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Biotin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Biotin
| Industry | Application | Process |
|---|---|---|
| Food | Nutritional fortificant | Added to food products to supplement vitamin B7 |
| Pharmaceuticals | Vitamin supplement | Formulated into tablets, capsules, or liquid dosage forms for human supplementation |
| Pharmaceuticals | Dermatological treatment | Applied in the treatment of skin disorders such as seborrheic dermatitis |
| Animal feed | Pet nutrition supplement | Added to pet food to support healthy coat development |
| Animal feed | Livestock nutrition supplement | Added to animal feed to enhance growth performance |
| Cosmetics | Skincare ingredient | Incorporated into skincare formulations to improve skin health and moisturization |
| Biotechnology | Microbial culture medium component | Used as an essential vitamin in microbial cultivation processes |
| Research laboratories | Research reagent | Employed in biochemical assays and analytical testing |
Manufacturing Quality Control of D-Biotin
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase chromatographic column and UV detector (approximately 200–210 nm), quantification is performed using external standard or area normalization method, providing high accuracy and good reproducibility. |
| Microbial Method (e.g., Lactobacillus Method) | Utilizes microorganisms sensitive to biotin (e.g., Lactobacillus plantarum) to assess growth response for total biological activity evaluation. | |
| Identification Test | Infrared Spectroscopy (IR) | Compare the sample's IR spectrum with that of the reference standard; confirm structure by matching characteristic absorption peaks. |
| Thin-Layer Chromatography (TLC) | Spot the sample on a TLC plate and compare Rf values with those of the standard. Observe spot positions using color-developing agents (e.g., iodine vapor) for identification. | |
| Related Substances/Impurity Check | HPLC Method (Gradient Elution) | Use a high-sensitivity detector (e.g., UV or CAD) to separate the main component from related impurities (e.g., biotin sulfoxide, degradation products, etc.). |
| Loss on Drying | Oven-Drying Method (105°C Constant Weight) | Weigh the sample in a pre-dried weighing bottle and dry at 105°C for several hours to calculate the percentage weight loss. |
| Residue on Ignition | High-Temperature Ashing Method | Ignefy the sample in a muffle furnace at 600–800°C until constant weight is achieved to determine inorganic residue content and assess inorganic impurity levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine the levels of limited elements (e.g., lead, arsenic, cadmium, mercury) after sample digestion to meet pharmacopoeia or food additive safety standards. |
| Optical Rotation | Polarimetry | Determine optical rotation by measuring a solution of defined concentration at a specified wavelength (typically sodium D-line, 589.3 nm) to verify optical purity. |
| pH Value | pH Meter Method | Measure pH directly after dissolving the sample in water using a calibrated pH meter to control the stability of the acidic-basic environment. |
| Solution Clarity and Color | Naked-Eye Color Comparison or Spectrophotometry | Compare with standard turbidity/color solutions or measure absorbance at specific wavelengths to evaluate appearance quality. |
Technical Specifications of D-Biotin
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 229~233°C |
| Optical Rotation | +89.5 to +91.5° (c=1 in 0.1 mol/L NaOH) |
| Total Impurities | <=2.0% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Biotin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Biotin
Packaging of D-Biotin
Industrial D-Biotin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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