China Factory Direct
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| CAS number | 580-19-8 |
| Product name | 7-Aminoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antimalarial drugs, used in the synthesis of 4-aminoquinoline derivatives such as chloroquine and hydroxychloroquine | Diazotization with sodium nitrite/hydrochloric acid, followed by reduction or coupling to construct the target molecular scaffold |
| Agrochemicals | Intermediate for insecticides and fungicides, incorporated into heterocyclic agrochemical molecules | Serves as a core heterocyclic scaffold; active side chains are introduced via N-alkylation, C-halogenation, or Suzuki coupling |
| Dyes & Pigments | Intermediate for fluorescent dyes and metal-complex dyes | Condensation with aldehydes to prepare Schiff base dyes, or coordination with metal ions (e.g., Al³⁺, Zn²⁺) to form stable fluorescent complexes |
| Analytical Chemistry | Component of fluorescent probes for metal ions and pH indicators | Leverages its weak basicity (pKa ≈ 4.9) and conjugated quinoline ring structure; protonation/deprotonation at specific pH values induces changes in fluorescence intensity or emission wavelength |
| Organic Synthesis | Multifunctional heterocyclic building block for constructing quinoline-based functional materials | Structural modification achieved via electrophilic substitution at C2/C4, alkylation/acylation at N1, or transition-metal-catalyzed C–H activation |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, toluene, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water by stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; quantifies Pb, Cd, Hg, As, and other regulated metals by atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C for 2 hours, indicating volatile content including residual moisture and low-boiling impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light in solution to confirm chiral integrity and absence of racemization. |
| Test Item | Specification |
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| Appearance | White to orange crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 54–58°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.