China Factory Direct
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| CAS number | 58123-62-9 |
| Product name | 1-Methyl-D-Proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of various pharmaceuticals, including antiviral agents. |
| Medical Research | Biochemical Research | Serves as an amino acid building block in protein and peptide synthesis. |
| Biotechnology | Enzyme Inhibitor Research | Applied to investigate specific enzyme mechanisms and develop novel enzyme inhibitors. |
| Personal Care Industry | Whitening Agent | Functions as an active ingredient in certain skin-lightening products to help reduce hyperpigmentation. |
| Materials Science | Polymer Modification | Used to prepare polymer materials with tailored properties, enhancing their physical or chemical characteristics. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 200-220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase to resolve N-methyl-D-proline from its L-enantiomer. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (500-600 C) followed by weighing of residual solids. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using an anion-exchange column with suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate ions using an anion-exchange column with suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., N-methyl-L-proline, proline, N-methyl-2-pyrrolidone) using gradient HPLC. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Measurement of hydrogen ion activity using a calibrated glass electrode in a standardized aqueous solution. |
| Specific Optical Rotation | Polarimetry | Determination of chiral compound concentration and enantiomeric identity via measurement of plane-polarized light rotation in solution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection by observing solid-to-liquid phase change under controlled heating rate. |
| Organic Volatile Impurities | GC-FID | Qualitative and quantitative analysis of residual solvents using gas chromatography with flame ionization detection. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.5% (NMR) |
| Optical Rotation | +95.0 to +100.0° (c=1, in H2O) |
| Melting Point | 220 to 225°C (decomposes) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.