3-chloro-4-iodobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 58123-72-1 |
| Product name | 3-chloro-4-iodobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-chloro-4-iodobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-chloro-4-iodobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-chloro-4-iodobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of drug intermediates | Used as a halogenated aromatic carboxylic acid building block in coupling, amidation, or esterification reactions to construct anticancer, anti-inflammatory, or central nervous system drug molecules |
| Agrochemicals | Synthesis of high-performance fungicide or insecticide intermediates | Applied in nucleophilic substitution or metal-catalyzed cross-coupling reactions to incorporate the chloro-iodobenzoic acid scaffold into heterocyclic or aromatic amine structures, enhancing biological activity |
| Chemical Reagents | High-purity organic synthesis building blocks | Used in laboratory-scale Suzuki, Heck, or Ullmann coupling reactions as structurally diverse precursor compounds |
| Materials Science | Preparation of functionalized conjugated polymers or liquid crystal material precursors | Applied after carboxyl group activation in amidation or esterification with amines or alcohols to construct aromatic polymers with optoelectronic properties |
Manufacturing Quality Control of 3-chloro-4-iodobenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., 3-chlorobenzoic acid, 4-iodobenzoic acid, residual starting materials) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection due to AgCl precipitation. |
| Iodide Content | IC (Ion Chromatography) | Anion-exchange separation followed by suppressed conductivity detection to quantify iodide ion released via alkaline oxidative hydrolysis. |
| Loss on Drying (LOD) | Gravimetric (105 °C, 2 h) | Mass loss measured after drying under standardized temperature and time to determine volatile content including water and residual solvents. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Residue on Ignition (Sulfated Ash) | Gravimetric (500–600 °C) | Mass of inorganic residue remaining after high-temperature incineration following sulfuric acid treatment, indicating inorganic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dispersed dry or wet samples. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with sample water in anhydrous methanol-based reagent. |
| pH of Aqueous Suspension (1% w/v) | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension, indicating acidic character and potential hydrolytic degradation. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, confirming absence of chiral contaminants (though compound is achiral, used for identity verification). |
Technical Specifications of 3-chloro-4-iodobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 174–178 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-chloro-4-iodobenzoic acid
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-chloro-4-iodobenzoic acid
Packaging of 3-chloro-4-iodobenzoic acid
Industrial 3-chloro-4-iodobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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