China Factory Direct
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| CAS number | 5813-89-8 |
| Product name | 2-THIOPHENECARBOXAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Intermediate for synthesizing antiviral, antibacterial, or antitumor agents | Used to construct active molecular scaffolds containing a thiophene ring; participates in organic synthesis reactions such as amidation and condensation |
| Agrochemicals | Agrochemical intermediate for synthesizing biologically active thiophene derivatives | Introduces the thiophene carboxamide structural unit via nucleophilic substitution or metal-catalyzed coupling reactions |
| Organic Synthesis | Key precursor for constructing thiophene-based functional molecules | Participates in synthetic pathways including Suzuki coupling and downstream transformations of Vilsmeier-Haack formylation |
| Materials Science | Used to prepare thiophene-based polymers or ligands with optoelectronic properties | Serves as a monomer or ligand precursor, incorporated into functional material systems via polymerization or coordination reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~230–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., 2-thiophenecarboxylic acid, 2-bromothiophene) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS or AAS (after acid digestion) | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg) following microwave-assisted nitric acid digestion and detection by inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by ignition at 700–800 °C followed by precise weighing of residual non-volatile material. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, reflecting crystallinity and purity. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared to platinum-cobalt standards. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions via suppressed conductivity detection (IC) or argentometric titration with silver nitrate endpoint detection. |
| pH of Aqueous Suspension | pH Meter Measurement | Measurement of pH in a defined saturated aqueous suspension (e.g., 1% w/v) using calibrated pH electrode, indicating acidic/basic impurity profile. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory after dispersion in air or inert gas. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 128-132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.