4-Methyl-3-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5832-44-0 |
| Product name | 4-Methyl-3-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-3-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-3-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-3-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a key synthetic building block in the reduction synthesis of 3-amino-4-methylpyridine, which is subsequently used to manufacture neurological therapeutics (e.g., safinamide for Parkinson’s disease) and other active pharmaceutical ingredients. |
| Pharmaceutical Chemicals | Piperidine Derivative Synthesis | Applied in the synthesis of functionalized N-alkylpiperidines or pyridinopiperidine derivatives, serving as core scaffolds in drug molecules. |
| Agrochemicals | Agrochemical Intermediate | Used to synthesize pyridine-ring-containing agrochemical active ingredients, contributing to molecular frameworks with insecticidal or fungicidal activity. |
| Organic Synthesis | Organic Synthesis Reagent | Leverages the electrophilic substitution reactivity of the nitro group and subsequent functional group transformations (e.g., reduction to amino, diazotization), enabling construction of complex nitrogen-containing heterocyclic compounds. |
| Scientific Research | Chemical Reagent | Employed in laboratory-scale mechanistic studies of chemical reactions and the development of novel heterocyclic compound syntheses. |
Manufacturing Quality Control of 4-Methyl-3-nitropyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260-280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., isomers, nitro reduction products) using gradient HPLC-UV; identification via retention time matching and/or spiked standards. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to quantify water content based on stoichiometric reaction with iodine and sulfur dioxide in pyridine-methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion, measuring atomic emission intensities at characteristic wavelengths for Pb, Cd, Hg, As, and Ni. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on anion-exchange column with suppressed conductivity detection; quantified against sodium chloride calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Sample charred with sulfuric acid, then ignited at 700 C; ash weight expressed as % of original sample. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change; reported as onset and clear point. |
| Organic Volatile Impurities | GC-FID | Headspace or direct injection GC with flame ionization detection to identify and quantify residual solvents (e.g., methanol, acetone, ethyl acetate). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard white background under controlled lighting; must be off-white to light yellow crystalline solid. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator; measures free acidic impurities (e.g., carboxylic acids, residual HNO3). |
| Bulk Density | Graduated Cylinder Method | Mass of material poured into calibrated cylinder divided by its settled volume; measured in g/mL after tapping to standard density. |
Technical Specifications of 4-Methyl-3-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 58–62°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-3-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-3-nitropyridine
Packaging of 4-Methyl-3-nitropyridine
Industrial 4-Methyl-3-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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