Ethyl 4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 583878-42-6 |
| Product name | Ethyl 4-Chloro-6-methyl-2-(methylthio)pyrimidine-5-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 583878-42-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 583878-42-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 583878-42-6
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing the broad-spectrum fungicide trifloxystrobin | Condensation with methyl 3-methoxyacrylate under alkaline conditions, followed by cyclization, hydrolysis, and esterification to produce trifloxystrobin |
Manufacturing Quality Control of 583878-42-6
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., hydrolysis products, isomers, starting materials) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, achieving sub-ppb sensitivity per ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion-specific separation and quantification (IC) or argentometric titration with AgNO₃ endpoint detection for inorganic chloride impurities. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration followed by sulfuric acid treatment and weighing of non-volatile inorganic residue per USP <281>. |
| Optical Rotation | [α]D Measurement | Polarimetric measurement at 589 nm to confirm chiral integrity and absence of racemization (though compound is achiral, verifies absence of chiral contaminants). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis to verify identity and crystallinity; deviation indicates polymorphic or impurity-related effects. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by light scattering analysis to ensure batch-to-batch consistency in solid-state handling properties. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in standardized aqueous suspension (e.g., 1% w/v) to assess acidic/basic degradation propensity and formulation compatibility. |
| Microbial Limits | Membrane Filtration + Culture | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of 583878-42-6
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 42–46°C |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 583878-42-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 583878-42-6
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Industrial 583878-42-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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