METHYL 2-CHLOROISONICOTINATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 58481-11-1 |
| Product name | METHYL 2-CHLOROISONICOTINATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYL 2-CHLOROISONICOTINATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL 2-CHLOROISONICOTINATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYL 2-CHLOROISONICOTINATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antitubercular agents and other bioactive molecules containing pyridine structures | Employed as an acylating agent or for constructing pyridine ring side chains, participating in nucleophilic substitution or coupling reactions |
| Agrochemical Intermediates | Synthesis of pyridine-carboxylic acid–based insecticides or herbicides | Functional group introduction via transesterification or ammonolysis |
| Organic Synthesis | Key building block for synthesizing 2-substituted pyridine derivatives | Reaction with nucleophiles such as amines and alcohols under basic conditions to yield corresponding amides or esters |
Manufacturing Quality Control of METHYL 2-CHLOROISONICOTINATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify methanol, dichloromethane, and other process solvents against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free acid content from hydrolysis byproducts. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 750 C followed by weighing of non-volatile inorganic residue to assess inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral purity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values per ISO 13320. |
Technical Specifications of METHYL 2-CHLOROISONICOTINATE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYL 2-CHLOROISONICOTINATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYL 2-CHLOROISONICOTINATE
Packaging of METHYL 2-CHLOROISONICOTINATE
Industrial METHYL 2-CHLOROISONICOTINATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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