Rebaudioside A Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 58543-16-1 |
| Product name | Rebaudioside A |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Rebaudioside A
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Rebaudioside A Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Rebaudioside A
| Industry | Application | Process |
|---|---|---|
| Food | Natural sweetener for low-sugar or sugar-free beverages, confectionery, and baked goods | Plant extraction and purification |
| Dietary Supplements | Sugar substitute in dietary supplements for blood glucose management or weight control | Fermentation or synthesis, followed by formulation processing |
| Pharmaceuticals | Excipient to improve palatability of oral medications; sweetening agent for diabetic patients | Chemical modification and formulation preparation |
| Personal Care | Sweetening agent in toothpaste, lip balm, and similar products, replacing conventional sugars | Blending and emulsification |
| Agriculture | Component of plant growth regulators (under research) | Biosynthesis and compound formulation |
Manufacturing Quality Control of Rebaudioside A
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 column is used, with water-acetonitrile or water-methanol as the mobile phase in gradient elution. The peak area of Rebaudioside A is detected by a UV detector (usually at around 210 nm), and quantified by external or internal standard method. This method offers high sensitivity, good repeatability and accuracy, and is the most commonly used method in pharmacopoeias and industry standards. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Similar to content determination, purity is calculated based on the percentage of the main peak area relative to the total peak area. It can simultaneously detect other steviol glycoside impurities (e.g., Rebaudioside D, M, etc.) and evaluate the overall sample purity. |
| Related Substances / Impurity Check | High-Performance Liquid Chromatography (HPLC) | Chromatographic conditions with high resolution are used to identify and quantify possible related impurities (e.g., other steviol glycosides, degradation products). Impurity limits are typically set (e.g., individual impurity ≤1.0%, total impurities ≤2.0%). |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, headspace injection gas chromatography (HS-GC) is used to detect residual organic solvents possibly present from the manufacturing process (e.g., methanol, ethanol, acetone), with FID detector for quantification. |
| Loss on Drying | Gravimetric Method after Drying | The sample is dried at 105°C to constant weight, and the percentage of mass loss is measured. This test controls moisture and volatile components, with a typical specification of ≤5.0%. |
| Residue on Ignition | High-Temperature Ashing Method | After ignition at high temperature (about 600–800°C), the remaining inorganic residue is weighed to control inorganic impurities, typically with a requirement of ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, AAS or the more sensitive ICP-MS is used to determine the content of heavy metals such as lead, arsenic, cadmium, and mercury, meeting food safety or pharmaceutical excipient limit requirements (e.g., total heavy metals ≤10 ppm). |
| Microbial Limits | Microbial Culture Method | Total aerobic microbial count, mold and yeast counts, and controlled organisms (e.g., Escherichia coli, Salmonella) are tested according to the Chinese Pharmacopoeia or USP general chapters to ensure microbial safety of the product. |
| Specific Optical Rotation | Polarimetry | A solution of defined concentration is prepared, and the optical rotation is measured under specified temperature and wavelength (usually the sodium D line, 589 nm). The specific optical rotation is then calculated for identification and assessment of optical purity. |
| Identification Test | Thin-Layer Chromatography (TLC) or Infrared Spectroscopy (IR) | TLC: Comparison of Rf values with reference standards after development on a silica gel plate and visualization. IR: Determination of characteristic functional group absorption peaks (e.g., hydroxyl, glycosidic bond), used for preliminary identification of Rebaudioside A. |
Technical Specifications of Rebaudioside A
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -36.0 to -30.0 deg (c=1, in methanol) |
| Melting Point | 194 to 198 °C |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Rebaudioside A
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| Lot/Batch Number | *Required fields | |
NMR Spectra of Rebaudioside A
Packaging of Rebaudioside A
Industrial Rebaudioside A Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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