4-Bromocumene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 586-61-8 |
| Product name | 4-Bromocumene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromocumene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromocumene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromocumene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key aryl bromide precursor for synthesizing anti-inflammatory agents, antiallergic drugs, and selective β2-adrenergic receptor agonists (e.g., salbutamol analogues) | Prepared via bromination—commonly starting from 4-isopropylphenol or 4-isopropylaniline using diazotization–Sandmeyer reaction or direct bromination (Br₂/FeBr₃ or NBS); subsequently employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct C–C bonds |
| Agrochemical Intermediates | Hydrophobic aryl structural unit for synthesizing novel pyrethroid insecticides and plant growth regulators | Prepared via Grignard reagent formation or lithium–halogen exchange, followed by reaction with electrophiles such as CO₂, aldehydes, or ketones to introduce functional groups (e.g., carboxy, hydroxymethyl); further modified via acid chloride formation, esterification, or amidation |
| Organic Synthesis Reagents | Aryl bromide used in transition metal-catalyzed C–C and C–N bond formation; widely applied in structural modification of functional materials and liquid crystal monomers | Reacted with aryl boronic acids (Suzuki coupling), alkenes (Heck reaction), or amines (Buchwald–Hartwig amination) under catalysis by Pd(PPh₃)₄ or Pd(dppf)Cl₂; alternatively, subjected to low-temperature lithiation with n-butyl lithium followed by electrophilic quenching |
Manufacturing Quality Control of 4-Bromocumene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile residue determined after high-temperature ashing at 700-800 C in a muffle furnace. |
| Acidity (as HBr) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of metal impurities after acid digestion by measuring absorbance at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using suppressed conductivity detection after aqueous extraction. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Measurement of yellowness intensity by matching sample color to APHA platinum-cobalt standards or absorbance at 430 nm. |
| Density at 20 C | Digital Density Meter | Determination of mass per unit volume using oscillating U-tube principle calibrated with air and water. |
| Refractive Index at 20 C | Refractometry | Measurement of light bending angle at air-sample interface using Abbe refractometer or digital equivalent. |
| Boiling Range | Distillation with Thermometer | Determination of temperature interval over which 90% of sample distills under controlled atmospheric pressure. |
| Non-Volatile Residue | Evaporation and Gravimetry | Weighing residue remaining after gentle evaporation of a fixed sample volume on a pre-weighed dish. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution in a defined cell pathlength and concentration. |
Technical Specifications of 4-Bromocumene
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.532–1.536 |
| Relative Density (20°C/25°C) | 0.995–1.005 g/cm³ |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromocumene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromocumene
Packaging of 4-Bromocumene
Industrial 4-Bromocumene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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