alpha-Angelica lactone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 591-12-8 |
| Product name | alpha-Angelica lactone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for alpha-Angelica lactone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk alpha-Angelica lactone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of alpha-Angelica lactone
| Industry | Application | Process |
|---|---|---|
| Fine Fragrances & Flavors | Natural fragrance ingredient used in formulating herbal, woody, or spicy fragrance compositions | Obtained via natural extraction or chemical synthesis; incorporated into fragrance formulations for personal care and food applications |
| Pharmaceuticals | Pharmaceutical intermediate or candidate active pharmaceutical ingredient (API) with potential anti-inflammatory and antioxidant bioactivity | Used in drug discovery for derivative synthesis and pharmacological activity screening |
| Personal Care & Cosmetics | Functional additive with potential skin-conditioning or antioxidant properties | Incorporated into skincare formulations, typically at low concentrations and in combination with other active ingredients |
| Research & Development | Reference standard or analytical control for chromatographic analysis, metabolic studies, and natural products chemistry | Applied in laboratory method development, plant metabolic pathway investigation, and structure–activity relationship (SAR) studies |
Manufacturing Quality Control of alpha-Angelica lactone
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with gradient elution employing methanol-water or acetonitrile-water as the mobile phase. Detection is performed at 275–280 nm using a UV detector for quantitative analysis of ligustilide. This method is sensitive, accurate, and reproducible, making it suitable for quantitative analysis of ligustilide in herbal materials and formulations. |
| Gas Chromatography (GC) | Suitable for detection of volatile components. After proper extraction and derivatization, samples are separated on a capillary column and detected by a flame ionization detector (FID). It can be used to analyze volatile oil constituents such as ligustilide in Angelica sinensis, although thermally unstable compounds may decompose during analysis. | |
| Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) | Combines high-resolution separation with high-sensitivity detection, ideal for qualitative and quantitative analysis of trace amounts of ligustilide in complex matrices. Particularly useful in pharmacokinetic studies or simultaneous multi-component analysis. | |
| Identification | Thin-Layer Chromatography (TLC) | Uses silica gel G plates with developing solvents such as hexane-ethyl acetate (e.g., 7:3). After development, fluorescent spots are observed under UV light (254 nm or 365 nm), or visualized using coloring reagents like vanillin-sulfuric acid. Used for preliminary identification of ligustilide in Angelica sinensis. |
| Infrared Spectroscopy (IR) | Involves infrared scanning of extracts and comparing characteristic absorption peaks of reference ligustilide (e.g., C=O stretching vibration of the lactone ring around 1760 cm⁻¹) for structural confirmation. | |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Structural analysis via ¹H-NMR and ¹³C-NMR spectra provides precise molecular information. Commonly used for reference standard verification or identification of novel compounds, though high cost limits its use in routine testing. | |
| Impurity Testing | HPLC Method | Evaluates related substances in ligustilide raw materials or formulations based on separation between the main component peak and impurity peaks to assess purity. Can employ peak area normalization or external standard methods for limit control. |
| Residual Solvent Testing | Gas Chromatography (GC) | Conducted according to the residual solvent determination method in the Chinese Pharmacopoeia to detect organic solvents (e.g., ethanol, benzene derivatives) remaining from the extraction process, ensuring compliance with safety limits. |
Technical Specifications of alpha-Angelica lactone
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC, mixture of isomers) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15° to -25° (c=1 in chloroform) |
| Refractive Index (n20/D) | 1.495–1.505 |
| Odor | Characteristic sweet, herbaceous odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of alpha-Angelica lactone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of alpha-Angelica lactone
Packaging of alpha-Angelica lactone
Industrial alpha-Angelica lactone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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