BOC-DL-PRO-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 59433-50-0 |
| Product name | BOC-DL-PRO-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-DL-PRO-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-DL-PRO-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-DL-PRO-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a chiral amino acid derivative for synthesizing proline-containing drug molecules (e.g., ACE inhibitors, antiviral agents) | Used as a protecting group to protect the amino group of proline during solid-phase or solution-phase peptide synthesis, preventing side reactions; deprotection is subsequently achieved under acidic conditions |
| Chemical Synthesis | Employed as a chiral building block or intermediate for constructing pyrrolidine ring structures in complex organic molecules | In multistep organic synthesis, Boc-protected DL-proline undergoes condensation, cyclization, or coupling reactions to control stereochemistry |
| Biochemical Research | Used to study the role of proline in protein folding, stability, and conformation | Served as a reference standard or synthetic precursor for preparing isotopically labeled or fluorescently labeled proline derivatives for enzymology and structural biology studies |
Manufacturing Quality Control of BOC-DL-PRO-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of Boc-DL-proline enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent where water reacts stoichiometrically, enabling precise quantification by endpoint detection. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection to quantify common solvents (e.g., dichloromethane, ethyl acetate) against calibration standards. |
| Heavy Metals | ICP-MS | Multi-element detection via inductively coupled plasma mass spectrometry after acid digestion; provides sub-ppb sensitivity for metals like Pb, Cd, Hg, As. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues using inductively coupled plasma optical emission spectroscopy after microwave-assisted digestion. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous extract; quantified using external calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 750 C to oxidize organic matter, followed by sulfuric acid treatment and final weighing of inorganic residue. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) in specified solvent and concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to derive volume-based particle size distribution in dry or dispersed state. |
| Microbial Contamination | Membrane Filtration | Filtration of sample solution followed by incubation on selective agar media; enumeration of CFUs per gram. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities (e.g., Boc-L-proline, Boc-D-proline, de-Boc-proline) using gradient HPLC with UV detection. |
Technical Specifications of BOC-DL-PRO-OH
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +/- 0.5° (c=1, in 1M HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-DL-PRO-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-DL-PRO-OH
Packaging of BOC-DL-PRO-OH
Industrial BOC-DL-PRO-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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