2-Amino-5-bromopyrazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 59489-71-3 |
| Product name | 2-Amino-5-bromopyrazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Amino-5-bromopyrazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Amino-5-bromopyrazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Amino-5-bromopyrazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Raw material for synthesizing anticancer agents, including kinase inhibitors (e.g., ALK and c-Met inhibitors) | Serves as a key intermediate in constructing drug molecular scaffolds via Suzuki coupling and nucleophilic substitution reactions |
| Pharmaceuticals | Raw material for synthesizing nicotinamide receptor agonists and drugs for inflammatory or neurological disorders | Introduces specific pharmacophores via condensation reactions or functional group transformations |
| Materials Science | Used to prepare organic optoelectronic functional materials or ligands | Modifies molecular structure through coupling reactions to tune electronic properties or serve as metal ligands |
| Chemical/Synthesis | Used to construct pyrazine-based heterocyclic compound libraries | Serves as a versatile synthetic building block, derivatized via functionalization reactions |
Manufacturing Quality Control of 2-Amino-5-bromopyrazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., 2-amino-pyrazine, bromination by-products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on the quantitative reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion at 700-800 C followed by weighing of the cooled ash. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via comparison to reference material. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards (e.g., white to off-white crystalline powder). |
| Loss on Drying | Thermogravimetric Analysis | Measures weight loss upon heating at 105 C for 2 hours, reflecting volatile content including residual moisture and low-boiling impurities. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity and identity by measuring rotation of plane-polarized light at 20 C using sodium D-line (589 nm). |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a 1:10 w/v suspension in purified water using calibrated pH electrode and temperature compensation. |
Technical Specifications of 2-Amino-5-bromopyrazine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Amino-5-bromopyrazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Amino-5-bromopyrazine
Packaging of 2-Amino-5-bromopyrazine
Industrial 2-Amino-5-bromopyrazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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