D-Alanine tert-butyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 59531-86-1 |
| Product name | D-Alanine tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Alanine tert-butyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Alanine tert-butyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Alanine tert-butyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing β-lactam antibiotics (e.g., penicillins, cephalosporins) | Used in peptide synthesis to incorporate D-alanine residues, typically via solid-phase or solution-phase coupling reactions |
| Pharmaceuticals | Synthesis of antiviral agents and antimicrobial peptides | Employed as a protected amino acid derivative; the tert-butyl ester protecting group is cleaved under mild acidic conditions to enable selective functional group transformation |
| Biochemical Research | Preparation of model peptides containing D-amino acids to study enzyme stereoselectivity toward D/L-configurations | The hydrochloride salt form is utilized to enhance aqueous solubility and stability, facilitating precise stereochemical control during peptide chain elongation |
| Agricultural Chemicals | Synthetic building block for certain peptidomimetic pesticides | Integrated into the construction of bioactive molecular scaffolds with defined spatial configurations to improve biological target specificity and metabolic stability |
Manufacturing Quality Control of D-Alanine tert-butyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Alanine tert-Butyl Ester Hydrochloride) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH using phenolphthalein indicator; endpoint corresponds to neutralization of HCl salt. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; quantifies D-isomer purity via peak area ratio. |
| Loss on Drying (LOD) | Gravimetric Analysis | Measures weight loss after drying under controlled temperature and vacuum; reflects volatile impurities and residual solvents. |
| Residual Solvents (e.g., tert-Butanol, DCM, EtOAc) | Gas Chromatography (GC-FID) | Separates and quantifies volatile organic solvents using flame ionization detection against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-OES | Digests sample in acid matrix and measures elemental emission intensities at characteristic wavelengths for multi-element quantification. |
| Chloride Content | Potentiometric Titration | Determines chloride ion concentration via titration with AgNO3 using silver electrode; endpoint detected by potential inflection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric reaction with iodine generated in situ via stoichiometric redox reaction. |
| pH of Aqueous Solution | pH Potentiometry | Measures hydrogen ion activity in 1% w/v aqueous suspension using calibrated glass electrode and reference electrode. |
| Related Substances (Impurities) | Reverse-Phase HPLC | Separates and quantifies structurally related impurities (e.g., D-alanine, tert-butyl alcohol, dipeptide byproducts) using UV detection at 210 nm. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles or discoloration against established reference standard under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range at which solid transitions to liquid using calibrated melting point apparatus; indicates purity and identity. |
| Bulk Density | Volumetric Measurement | Measures mass per unit volume of freely settled powder in standardized cylinder; correlates with flow and handling properties. |
Technical Specifications of D-Alanine tert-butyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | -1.0 to -2.0 deg (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Alanine tert-butyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Alanine tert-butyl ester hydrochloride
Safety Information of D-Alanine tert-butyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-Alanine tert-butyl ester hydrochloride
Industrial D-Alanine tert-butyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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