China Factory Direct
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| CAS number | 59702-31-7 |
| Product name | 1-Ethyl-2,3-dioxopiperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a pharmaceutical intermediate for synthesizing biologically active compounds | Combined with the 2,3-diketopiperazine scaffold via ethylation, followed by functionalization |
| Biochemical Research | Employed as a model compound for studying peptide analogs and cyclic molecular structures | Incorporated into target molecules using solid-phase or solution-phase peptide synthesis |
| Materials Science | Applied in developing novel functional polymers or crosslinkers | Participates in condensation or addition reactions via its diketone functionality to form polymeric networks |
| Chemical Reagents | Utilized as a specialized building block in organic synthesis | Subjected to selective reduction or coupling reactions under specific catalytic conditions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210–230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification of structurally related impurities (e.g., starting materials, degradation products) using gradient HPLC/UV or hyphenated UPLC-MS for specificity. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization or mass spectrometric detection to quantify volatile organic solvents (e.g., ethyl acetate, toluene, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying trace water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS or ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission or mass spectrometric detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Measurement of inorganic residue after controlled high-temperature incineration and sulfuric acid treatment, indicating inorganic impurities. |
| Optical Rotation | [α]D Measurement | Determination of specific rotation using a polarimeter at 589 nm (Na-D line) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis to verify identity and crystallinity by observing the temperature range of solid-to-liquid phase change. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension to assess acidic/basic impurities or degradation. |
| Particle Size Distribution | Laser Diffraction | Analysis of size distribution in dispersed powder sample using Mie theory-based light scattering principles. |
| Microbial Limits | Membrane Filtration & Culture | Quantitative enumeration of aerobic microorganisms, yeasts, and molds per pharmacopoeial methods (e.g., USP <61>). |
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.