China Factory Direct
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| CAS number | 597532-36-0 |
| Product name | Ethyl 6-(trifluoromethyl)nicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs; used in synthesizing kinase inhibitors based on trifluoromethyl-substituted nicotinic acid derivatives | Palladium-catalyzed cross-coupling (e.g., Suzuki or Heck reactions), followed by hydrolysis/ester exchange to construct quinoline or indazole scaffolds |
| Agrochemicals | Key structural motif in novel insecticides and herbicides, enhancing metabolic stability and target binding affinity | Multistep organic synthesis: functional group transformations (e.g., halogenation, nitration) followed by reduction and cyclization to introduce heterocyclic agrochemical cores |
| Materials Science | Precursor for electron-transport layer materials in organic light-emitting diode (OLED) devices | Purification as a vacuum-deposition precursor, or use as a trifluoromethylated electron-accepting monomer in solution-processed copolymerization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by retention time and peak area relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., ethanol, ethyl acetate) via capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration based on iodine consumption in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compound using sodium D-line light in solution at controlled temperature and concentration. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against standard white background under controlled lighting. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode system. |
| Bulk Density | USP <616> Tap Density Method | Determines mass per unit volume after standardized tapping of powder in graduated cylinder. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.