2,5-Dichloronicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 59782-85-3 |
| Product name | 2,5-Dichloronicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,5-Dichloronicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-Dichloronicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-Dichloronicotinic acid
| Industry | Application | Process |
|---|---|---|
| Agrochemicals | Insecticide intermediate | Serves as a key structural unit in the synthesis of neonicotinoid insecticides (e.g., thiamethoxam, clothianidin) as an intermediate or derivative. |
| Pharmaceuticals | Building block for drug molecules | Leverages its pyridine ring structure to construct biologically active drug molecules, primarily for synthesizing active pharmaceutical ingredients (APIs) with antiviral, antibacterial, or antitumor activity. |
| Organic synthesis | Carboxylic acid derivatization reagent | Used in esterification and amidation reactions via its carboxylic acid group to synthesize target compounds; alternatively, employed in decarboxylative chlorination to introduce chloropyridyl moieties. |
| Research & development | Active molecule screening | Applied in the construction and screening of small-molecule compound libraries for identifying candidates with potential biological activity. |
Manufacturing Quality Control of 2,5-Dichloronicotinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 230-254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of individual impurities above identification threshold. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver/silver sulfide electrode; endpoint detected by potential change due to AgCl precipitation. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particles or discoloration against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution via Mie scattering theory applied to dispersed particles in air or liquid medium. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode after equilibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution of known concentration and path length to assess chiral purity. |
Technical Specifications of 2,5-Dichloronicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,5-Dichloronicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-Dichloronicotinic acid
Packaging of 2,5-Dichloronicotinic acid
Industrial 2,5-Dichloronicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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