China Factory Direct
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| CAS number | 598-10-7 |
| Product name | 1,1-Cyclopropanedicarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthetic intermediate for drug synthesis | Used in the synthesis of drug molecules containing a cyclopropyl moiety, such as quinolone antibiotics (e.g., ciprofloxacin derivatives) and other active pharmaceutical ingredients (APIs). |
| Pharmaceutical Industry | Pharmacophore construction | Applied as a key building block to introduce the high-strain, rigid cyclopropyl group into drug molecules, thereby improving metabolic stability, enhancing potency, or reducing toxicity. |
| Pharmaceutical Industry | Synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) | Used in the synthesis of certain NSAIDs and analogues, where substitution with a cyclopropyl group optimizes pharmacokinetic properties. |
| Organic Synthesis | Specialized organic synthesis reagent | Serves as a dicarboxylic acid source; upon thermal decarboxylation (loss of one molecule of CO₂), yields 1-carboxycyclopropane or other cyclopropane derivatives. |
| Agrochemical Industry | Agrochemical intermediate | Applied in the synthesis of cyclopropane-containing fungicides, insecticides, or plant growth regulators to enhance penetration and biological activity. |
| Research Sector | Chemical biology research | Used to investigate the effect of the cyclopropyl functional group on enzyme inhibitory activity, and to develop novel inhibitors or probe molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination using reverse-phase HPLC and UV absorbance at 210 nm relative to a certified reference standard. |
| Water Content | Karl Fischer titration | Electrochemical titration based on the reaction of iodine with water in a methanol-based reagent. |
| Residue on Ignition | Gravimetric analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 750 C. |
| Heavy Metals | ICP-OES | Multi-element quantification of metal impurities by plasma excitation and optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and suppressed conductivity detector. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate anions using anion-exchange column and suppressed conductivity detector. |
| Related Substances | HPLC with UV detection | Identification and quantification of structurally related impurities using gradient HPLC and UV detection. |
| Melting Point | Capillary melting point apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary tube method. |
| Acid Value | Acid-base titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against specified standards under controlled lighting. |
| Solubility in Common Solvents | Qualitative dissolution test | Observation of complete dissolution in specified solvents (e.g., methanol, acetone) at room temperature. |
| Residual Solvents | Gas Chromatography (GC-FID) | Quantitative analysis of volatile organic solvents using flame ionization detection and headspace sampling. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Melting Point | 148-152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 320-340 mg KOH/g |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.