China Factory Direct
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| CAS number | 59857-86-2 |
| Product name | 1-Methyl-5-oxo-3-pyrrolidinecarboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in organic synthesis reactions |
| Agrochemicals | Preparation of active pharmaceutical ingredients (APIs) | Applied in chemical modification and structural optimization |
| Chemicals | Modifier for polymer materials | Applied in polymer functionalization |
| Fine Chemicals | Synthesis of specialty chemicals | Applied in targeted chemical transformations |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Optical Rotation | [alpha]D Measurement | Polarimetric measurement of specific rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of elemental impurities (e.g., Pb, Cd, Hg, As) at sub-pptr levels. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile residue after sulfuric acid treatment to assess inorganic impurity load. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; used for identity confirmation and purity screening. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Electrochemical measurement using calibrated pH electrode in a saturated aqueous suspension to assess acidic/basic degradation products. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference under controlled lighting and against white/black backgrounds. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values relevant for handling and formulation performance. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -25.0° (c=1, in methanol) |
| Solubility | Freely soluble in methanol, ethanol, and dichloromethane; slightly soluble in water |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.