4-Iodo-1H-indazol-3-ylamine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 599191-73-8 |
| Product name | 4-Iodo-1H-indazol-3-ylamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Iodo-1H-indazol-3-ylamine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Iodo-1H-indazol-3-ylamine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Iodo-1H-indazol-3-ylamine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Building block for small-molecule drug lead compounds and kinase inhibitors | Used as an intermediate in the synthesis of targeted anticancer drugs (e.g., BRAF and ALK inhibitors), where heterocyclic scaffolds are constructed via Suzuki coupling or reductive amination |
| Organic Synthesis | Functionalized indazole building block | Serves as a platform molecule for introducing iodine substituents in multistep syntheses; diversified indazole derivatives are prepared via metal-catalyzed cross-coupling reactions (e.g., Heck, Stille) |
| Materials Science | Precursor for organic optoelectronic materials | Used to synthesize indazole-based conjugated polymers with charge-transport properties; functional layers for OLED/OFET devices are prepared via palladium-catalyzed polymerization or condensation reactions |
Manufacturing Quality Control of 4-Iodo-1H-indazol-3-ylamine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, intermediates, degradants) via gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., DMF, acetone, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine consumption in a pyridine-methanol buffer system. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni, Cu) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Appearance | Visual Inspection | Evaluates physical state, color, and presence of foreign particles under controlled white light against standard reference. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by determining rotation angle of plane-polarized light passing through a solution of the compound. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser beam. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
Technical Specifications of 4-Iodo-1H-indazol-3-ylamine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 215–219 °C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Iodo-1H-indazol-3-ylamine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Iodo-1H-indazol-3-ylamine
Packaging of 4-Iodo-1H-indazol-3-ylamine
Industrial 4-Iodo-1H-indazol-3-ylamine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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