(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 601515-79-1 |
| Product name | (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of various drugs, including antibiotics and antineoplastic agents | Chemical synthesis, purification, crystallization |
| R&D | Applied in drug discovery and development for structural modification and biological activity testing | Laboratory-scale synthesis, analytical characterization |
Manufacturing Quality Control of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., diastereomers, dehydro, hydrolyzed products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization or mass spectrometric detection to quantify Class 2/3 solvents (e.g., methanol, ethyl acetate, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg, Ni) after acid digestion, per ICH Q3D, using inductively coupled plasma mass spectrometry or optical emission spectrometry. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Argentometric titration using silver nitrate and a silver indicator electrode; endpoint detected by potential inflection due to AgCl precipitation. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Separation on a chiral stationary phase (e.g., Chiralpak AD-H) with UV detection to determine % ee by comparing peak areas of (1R,4R) and (1S,4S) enantiomers. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 700–800 °C after sulfuric acid treatment; residual inorganic ash is weighed to assess inorganic impurity load. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in freshly prepared aqueous solution, reflecting protonation state and salt hydrolysis behavior. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via Mie scattering theory to determine D10, D50, D90 values relevant to dissolution and handling properties. |
Technical Specifications of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 182°C - 186°C |
| Optical Rotation | -113° to -100° (c=1, in H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
Safety Information of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane
Industrial (1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptane Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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