China Factory Direct
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| CAS number | 604-44-4 |
| Product name | 4-CHLORO-1-NAPHTHOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Dye Industry | Intermediate for azo dye synthesis | Used in diazotization-coupling reactions |
| Biochemistry | Substrate for enzyme-linked immunosorbent assay (ELISA) | Generates colored products with peroxidase |
| Pharmaceutical R&D | Precursor for drug synthesis | Applied in nucleophilic aromatic substitution of halogenated arenes |
| Analytical Chemistry | Colorimetric reagent and detection agent | Employed in oxidative color development reactions |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity/Assay | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (typically at 254 nm or 280 nm), the content of 4-chloro-1-naphthol is determined by external standard method or area normalization method to evaluate its purity. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Under the same or optimized chromatographic conditions as used in assay determination, organic impurities such as unreacted starting materials, by-products, and degradation products are separated and detected. Impurities are identified by comparison with reference standards or relative retention times, and their levels—both individual and total—are quantified and controlled within specified limits. |
| Melting Point | Capillary Melting Point Method | The sample is packed into a capillary tube and heated at a specified rate in a melting point apparatus. The initial and final melting temperatures are observed and recorded, then compared with the standard melting range (approximately 93–96 °C) to assess sample purity and consistency. |
| Appearance | Visual Inspection | The sample is examined under natural or standard lighting for color, physical state (typically white to light yellow crystalline powder), and presence of visible foreign matter, serving as a preliminary quality assessment. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying at Atmospheric Pressure | The sample is dried to constant weight at 105 °C, and the percentage weight loss is measured to evaluate moisture and volatile content, generally required to be ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Using headspace or direct injection with an FID detector, residual organic solvents from manufacturing (e.g., toluene, dichloromethane) are analyzed according to pharmacopoeial methods or ICH guidelines to ensure compliance with safety limits. |
| Heavy Metals / Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After acid digestion of the sample, levels of toxic elements such as lead, arsenic, cadmium, and mercury are measured to ensure compliance with regulatory requirements (e.g., USP <232>/<233> or ICH Q3D). |
| Test Item | Specification |
|---|---|
| Appearance | White to gray or brown crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.