China Factory Direct
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| CAS number | 605-38-9 |
| Product name | 2,3-Pyridinedicarboxylic acid dimethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as precursor compounds in the synthesis of antitumor, antibacterial, or neuroactive drugs | Employed as an organic synthetic building block in amidation, transesterification, or cyclization reactions to construct heterocyclic frameworks |
| Pesticide Chemistry | Serves as a synthetic intermediate for active ingredients in insecticides or herbicides | Introduces pyridinecarboxylic acid structural motifs via functional group transformations (e.g., hydrolysis, reduction) |
| Materials Science | Used in the preparation of metal-coordinated polymers or ligands for luminescent materials | Coordinates with transition metal ions (e.g., Cu²⁺, Zn²⁺) to form MOFs or fluorescent coordination complexes |
| Organic Synthesis Reagents | Acts as a dicarboxylate compound in cycloaddition reactions such as Diels–Alder | Functions as a dienophile in [4+2] cycloadditions, leveraging the electron-deficient nature of its pyridine ring |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities by eye; typically expected to be white to off-white crystalline powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as mobile phase under isocratic or gradient elution. The peak area of the main component is detected by UV detector (e.g., 254 nm) to calculate purity, typically required to be ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as purity testing. Potential impurities (e.g., unreacted starting materials, by-products, degradation products) are identified and quantified by comparing sample chromatograms with reference standards. Individual impurity typically ≤0.5%, total impurities ≤1.0%. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus or Thiele tube method. The typical melting point of dimethyl pyridine-2,3-dicarboxylate is approximately 70–74 °C, used to assess purity and consistency. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying at Atmospheric Pressure | Dry the sample to constant weight at 105 °C and measure the percentage weight loss to evaluate moisture and volatile content, typically required to be ≤0.5%. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ignition Method | Ignite the sample in a muffle furnace at 600–800 °C to constant weight and measure the inorganic residue to control inorganic impurities, typically required to be ≤0.1%. |
| Water Content | Karl Fischer Titration | Determine water content using volumetric or coulometric Karl Fischer titration, suitable for moisture-sensitive organic compounds, typically required to be ≤0.2%. |
| Infrared Spectroscopic Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Prepare KBr pellet or use ATR technique to obtain IR spectrum. Characteristic absorption peaks (e.g., ester carbonyl C=O around 1720 cm⁻¹, pyridine ring skeletal vibrations around 1600–1500 cm⁻¹) are compared with reference spectra to confirm molecular structure. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Nuclear Magnetic Resonance (NMR) Spectroscopy | Dissolve sample in deuterated solvent such as CDCl₃ and analyze chemical shifts and integration ratios of hydrogen atoms to verify molecular structure and detect potential isomers or impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.