China Factory Direct
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| CAS number | 60518-41-4 |
| Product name | 7-chloro-3,4-dihydroisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for synthesizing antipsychotic and antidepressant agents | Used as a key intermediate in multistep organic synthesis to construct the isoquinoline scaffold via substitution and cyclization reactions |
| Agrochemical Chemistry | Precursor for synthesizing novel active pharmaceutical ingredients (APIs) of pesticides | Applied in the synthesis of heterocyclic compounds with insecticidal or fungicidal activity, introducing functional groups via electrophilic substitution or coupling reactions |
| Polymer Materials | Monomer or modifier for functional polymer materials | Incorporated into polymer backbones via polymerization to enhance thermal stability and biocompatibility |
| Biomedical Research | Building block for drug molecule libraries and probe molecules | Employed as a structural motif in high-throughput screening and drug target validation, commonly modifying biomacromolecules via coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-DAD | Detects and quantifies impurities by HPLC with diode array detection, identifying peaks based on retention time and spectral match. |
| Residual Solvents | GC-FID | Measures volatile organic solvents using gas chromatography with flame ionization detection against internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Ion Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after eluent gradient separation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity based on sharpness and agreement with reference value. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under controlled temperature and vacuum, reflecting volatile content and residual moisture. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral molecules in solution, confirming enantiomeric identity and purity. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Evaluates acidity/basicity by measuring hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension by analyzing angular variation in laser light scattering intensity. |
| Residue on Ignition | Gravimetric Ash Test | Quantifies inorganic residue remaining after high-temperature combustion in a muffle furnace, indicating non-volatile inorganic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.