H-D-THR-OME HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 60538-15-0 |
| Product name | H-D-THR-OME HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-D-THR-OME HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-D-THR-OME HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-D-THR-OME HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of antibiotics, antiviral agents, and peptide-based drugs | Prepared via esterification and hydrochloride salt formation; employed in asymmetric synthesis or solid-phase peptide synthesis (SPPS) |
| Biochemical Research | Used to study amino acid metabolism, enzymatic reaction mechanisms, and structure–function relationships in proteins | Applied as a reference standard or substrate; analyzed and characterized using HPLC or enzyme kinetic assays |
| Chemical Synthesis | Used as a chiral building block for constructing complex organic molecules, such as natural products or drug lead compounds | Introduced into target molecular frameworks via protecting-group strategies, condensation, or coupling reactions in organic solvents |
Manufacturing Quality Control of H-D-THR-OME HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Threonine Methyl Ester Hydrochloride) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH using phenolphthalein indicator; accounts for HCl salt content. |
| Chiral Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; detection via UV absorbance at 210 nm. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric reaction with iodine, sulfur dioxide, and base in methanol. |
| Residual Solvents (Methanol, Ethyl Acetate) | Gas Chromatography (GC-FID) | Quantifies volatile organic solvents using flame ionization detection after headspace or direct injection. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (e.g., Pb, Cd, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant and silver/silver chloride electrode endpoint detection. |
| pH (1% aqueous solution) | pH Meter Measurement | Determines acidity of aqueous solution using calibrated pH electrode in deionized water suspension. |
| Specific Optical Rotation | Polarimetry | Measures degree of rotation of plane-polarized light at 20 C and 589 nm to confirm chiral integrity. |
| Related Substances | Reverse-Phase HPLC | Detects and quantifies impurities (e.g., D-threonine, methyl ester hydrolysis products) using C18 column and UV detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration at 700-800 C followed by weighing. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size by measuring angular scattering pattern of laser beam through dispersed sample. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of H-D-THR-OME HCL
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | +7.5 to +8.2° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-D-THR-OME HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-D-THR-OME HCL
Packaging of H-D-THR-OME HCL
Industrial H-D-THR-OME HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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