China Factory Direct
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| CAS number | 606-68-8 |
| Product name | NADH, disodium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Reagent for cellular metabolism studies | Used in in vitro cell assays as an NAD+ analog for enzyme activity detection |
| Biotechnology | Enzymatic reaction cofactor | Applied in laboratory settings as an auxiliary substrate for dehydrogenases and other enzymes in biochemical analysis |
| Cosmetics | Anti-aging ingredient research | Employed as an NAD+ precursor analog in studies of skin cell energy metabolism and repair mechanisms |
| Academic Research | Molecular biology tool | Used to investigate DNA repair, sirtuin protein activity, and associated signaling pathways |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of agglomeration. Typically appears as a white or off-white lyophilized powder with no visible foreign particles. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes the characteristic absorption peak of NAD⁺ at 260 nm (from adenine base) and strong absorption of reduced form (NADH) at 340 nm; identification is performed via spectral ratio analysis. |
| High-Performance Liquid Chromatography (HPLC) | Compares retention time with that of reference standard to confirm consistency of main peak, used for indirect structural identification. | |
| Content Determination | Ultraviolet Spectrophotometry (UV Method) | Measures absorbance at 260 nm and calculates content using molar extinction coefficient (ε ≈ 18,000 L·mol⁻¹·cm⁻¹). |
| High-Performance Liquid Chromatography (HPLC) | Quantifies the main component using external standard method or area normalization, offering high accuracy suitable for precise quantification. | |
| Purity (Related Substances) | High-Performance Liquid Chromatography (HPLC) | Detects degradation products such as NADH, NMN, and nicotinamide impurities; calculates relative peak areas of each impurity to assess purity. |
| Moisture (Loss on Drying) | Karl Fischer Titration | Accurately determines water content in the sample, especially critical for quality control of lyophilized products. |
| Residual Solvents | Gas Chromatography (GC) | Tests for potentially residual organic solvents (e.g., ethanol, acetone) from manufacturing processes, complying with ICH guidelines on residual solvents. |
| pH Value | pH Meter Measurement | Dissolve sample in water (e.g., 1% solution), then measure pH using a calibrated pH meter, controlled within specified range (e.g., 6.0–8.0). |
| Bacterial Endotoxins | Limulus Amebocyte Lysate (LAL) Assay | Tests for bacterial endotoxin levels, commonly used for injectable or biopharmaceutical-grade products; limit typically ≤0.5 EU/mg. |
| Microbial Limits | Microbial Limit Test | Includes testing for total aerobic bacteria count, total mold and yeast count, and control organisms (e.g., Escherichia coli), meeting pharmacopeial requirements. |
| Sulfated Ash (Charring Residue) | Gravimetric Method | After high-temperature incineration, the residue weight is measured to control inorganic impurity levels, typically ≤0.5%. |
| Sodium Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determines sodium ion content to verify the correctness of the disodium salt form and ensure proper stoichiometric ratio. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=20 ppm |
| Optical Rotation | -20.0 to -24.0 deg (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.