China Factory Direct
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| CAS number | 611-72-3 |
| Product name | DL-Mandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Chiral drug intermediates for synthesizing antibiotics (e.g., cephalosporins), anticancer agents, and cardiovascular drugs | Chiral resolution or asymmetric synthesis, commonly via enzymatic hydrolysis or chemical resolution of DL-mandelic acid esters to prepare single enantiomers |
| Agrochemicals | Synthetic intermediate for insecticides and fungicides | Participates in heterocycle construction, e.g., condensation with hydrazides to form precursors of triazole fungicides |
| Fine Fragrances | Fixative and fragrance modifier imparting soft floral notes | Used as an acylating agent or esterification feedstock to produce mandelic acid esters (e.g., ethyl mandelate) |
| Personal Care & Cosmetics | Skin-conditioning and keratolytic agent for exfoliating and skin-brightening formulations | Directly incorporated into emulsions and serums at typical concentrations of 0.5–2.0%, leveraging its α-hydroxy acid properties to promote epidermal renewal |
| Organic Synthesis | General chiral building block and resolving agent | Applied in dynamic kinetic resolution of chiral alcohols and amines; also serves as a chiral auxiliary in Diels–Alder and aldol reactions |
| Test Item | Common Test Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with methanol-water or buffer solution as the mobile phase, and a UV detector (e.g., 210 nm). DL-Mandelic acid content is quantified by external or internal standard method, offering high sensitivity and good reproducibility. |
| Purity Analysis | Gas Chromatography (GC) | Suitable for volatile derivatives. DL-Mandelic acid is derivatized (e.g., silylation), separated on a capillary column, and detected by FID to assess organic impurity levels. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs chiral stationary phase columns (e.g., Chiralpak series) to separate L- and D-mandelic acid enantiomers, enabling evaluation of enantiomeric excess (ee value) for control of optical purity. |
| Water Content | Karl Fischer Titration | Measures water content precisely based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment, using coulometric or volumetric methods. Widely used in raw material quality control. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Optimizes gradient elution programs based on assay conditions to separate and detect potential impurities such as synthesis intermediates and degradation products. Total impurity levels are typically required to be below specified limits. |
| Melting Point | Capillary Melting Point Determination | Sample is packed into a capillary tube and heated gradually in a melting point apparatus. The initial and final melting temperatures are observed. The typical melting point of DL-mandelic acid is approximately 117–120 °C, used for preliminary identification and purity assessment. |
| pH Value | pH Meter Method | The sample is dissolved in water to a specific concentration (e.g., 1% w/v), and the pH is measured using a calibrated pH meter to evaluate its acidic characteristics and stability. |
| Heavy Metals | Thioacetamide Method (Chinese Pharmacopoeia Method) | In weakly acidic conditions, heavy metal ions react with thioacetamide to form colored sulfides, which are measured colorimetrically. The total heavy metal content is typically limited to ≤20 ppm. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Sample is dried at a specified temperature (e.g., 105 °C) to constant weight, and the percentage weight loss is determined, reflecting moisture and volatile component content. |
| Sulfated Ash | Sulfated Ashing Method | Sample is incinerated at high temperature, treated with sulfuric acid, and the residual inorganic matter is weighed to determine inorganic impurity content. |
| Test Item | Specification |
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| Appearance | Crystalline Powder |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 118–122°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +/- 0.5° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.