China Factory Direct
|
|
| CAS number | 6113-61-7 |
| Product name | N-FORMYL-L-LEUCINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral synthetic intermediate for preparing peptide-based drugs and bioactive molecules | Formyl protecting group introduced via acylation or condensation reactions; employed in peptide chain elongation or modification |
| Biochemical Research | Used as an enzyme inhibitor or metabolic probe to study amino acid metabolic pathways | Acts as a substrate analog in in vitro enzymatic reaction systems to evaluate enzyme specificity and activity |
| Organic Synthesis | Used as a chiral auxiliary or building block in asymmetric synthesis | Chiral center directs stereoselective reactions, such as Diels–Alder and alkylation reactions |
| Analytical Chemistry | Used as a reference standard or derivatization reagent for amino acid analysis | Pre-column derivatization with target amino acids to enhance detection sensitivity and separation resolution in HPLC or GC |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with UV detection to calculate enantiomeric excess. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time, indicating volatile impurities and residual solvents. |
| Residual Solvents | GC-FID | Detection and quantification of common organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration based on precipitation endpoint. |
| Sulfated Ash | Gravimetric (550 C) | Residue mass after high-temperature incineration, indicating inorganic impurities including metal sulfates. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 C using sodium D-line, confirming chiral integrity and concentration. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension to assess acidity/basicity. |
| Related Substances | HPLC-UV (Gradient) | Detection and quantification of structurally related impurities (e.g., L-leucine, N-formyl-L-isoleucine) using gradient elution HPLC. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with KF reagent to quantify trace water based on stoichiometric iodine consumption. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | ≥99.0% |
| Water | ≤1.0% |
| Formic acid | ≤0.5% |
| N-formyl-L-isoleucine | ≤0.05% |
| Single impurity | ≤0.5% |
| Total impurities | ≤1.0% |
| Benzene | ≤2 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.