China Factory Direct
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| CAS number | 6125-57-1 |
| Product name | trans-Methyl4-hydroxycyclohexanecarboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidiabetic drug sitagliptin | Produced via reaction of cyclohexenone with methanol to yield trans-4-hydroxycyclohexanecarboxylic acid methyl ester, subsequently used to construct the cyclic scaffold of sitagliptin |
| Chemical Synthesis | Chiral intermediate in organic synthesis | Prepared via asymmetric catalytic hydrogenation or chiral resolution to achieve high optical purity of trans-4-hydroxycyclohexanecarboxylic acid methyl ester |
| Pesticides | Precursor in the synthesis of certain herbicides or insecticides | Serves as a synthetic intermediate for cyclohexane-containing pesticide molecules |
| Fragrances | Used in the synthesis of specific fragrance compounds | Introduced into target odor molecules via esterification or other organic synthesis pathways |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent where water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Residue weight measurement after high-temperature incineration of sample followed by sulfuric acid treatment and ignition. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm stereochemical identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate; used for identity and purity assessment. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established visual standards under controlled lighting conditions. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residue after microwave-assisted digestion using inductively coupled plasma optical emission spectroscopy. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless semi-solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 45–49°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.