4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 612501-80-1 |
| Product name | 4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 612501-80-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 612501-80-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 612501-80-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate | Used in organic synthesis |
| Pharmaceutical manufacturing | Synthesis of active pharmaceutical ingredients (APIs) | Applied in chemical synthesis |
| Organic synthesis | Synthesis of quinazoline compounds | Applied in amination, methoxylation, and esterification reactions |
Manufacturing Quality Control of 612501-80-1
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and base in methanol; water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-OES | Multi-element detection of metal impurities after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (600-800 C) to determine inorganic non-volatile impurities. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral centers in solution at specified wavelength and temperature. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate particle size distribution based on Mie or Fraunhofer theory. |
| pH of Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in aqueous suspension using calibrated glass and reference electrodes. |
| Microbial Limits | Membrane Filtration | Quantitative recovery of viable microorganisms from sample solution by filtration, followed by incubation on selective agar media. |
| Identity Confirmation | FTIR Spectroscopy | Verification of molecular structure by comparing sample infrared absorption spectrum to reference standard across functional group regions (e.g., C=O, N-H, C-Cl). |
Technical Specifications of 612501-80-1
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 612501-80-1
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 612501-80-1
Industrial 612501-80-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply