BOC-D-4-Nitrophe Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 61280-75-9 |
| Product name | BOC-D-4-Nitrophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-D-4-Nitrophe
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-D-4-Nitrophe Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-D-4-Nitrophe
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | As a non-natural amino acid building block for synthesizing peptide-based drugs | Introduced into peptides via solid-phase peptide synthesis (SPPS) to incorporate nitrophenylalanine residues; the Boc protecting group safeguards the amino functionality, enabling selective coupling |
| Biochemical Research | For site-specific modification in protein structure and function studies | Leverages the photoreactive or chemically reactive nitrophenyl ring for targeted labeling in photo-crosslinking experiments or probe design |
| Organic Synthesis | As a chiral intermediate in the construction of complex molecules | After Boc deprotection, subjected to amidation, alkylation, and other transformations to synthesize biologically active molecules with defined stereochemistry |
Manufacturing Quality Control of BOC-D-4-Nitrophe
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities (e.g., BOC-D-Phe, nitrophenyl derivatives) using gradient HPLC and UV detection. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration with iodine generated electrochemically in pyridine/methanol-based reagent. |
| Residual Solvents | GC-FID | Identifies and quantifies solvents (e.g., DMF, dichloromethane, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Determines trace metal contaminants (e.g., Pb, Cd, Ni, Fe) by inductively coupled plasma mass spectrometry after acid digestion. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions via suppressed conductivity detection after separation on an anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and laser diffraction analysis. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration per USP <61>. |
Technical Specifications of BOC-D-4-Nitrophe
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 168-172°C |
| Optical Rotation | -10.0 to -7.0° (c=1, in 1M HCl) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-D-4-Nitrophe
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-D-4-Nitrophe
Packaging of BOC-D-4-Nitrophe
Industrial BOC-D-4-Nitrophe Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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