1-Amino-4-cyclopentylpiperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 61379-64-4 |
| Product name | 1-Amino-4-cyclopentylpiperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Amino-4-cyclopentylpiperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Amino-4-cyclopentylpiperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Amino-4-cyclopentylpiperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for central nervous system (CNS) drugs, used in the synthesis of candidate 5-HT2A receptor antagonists | Used as a key chiral building block in multi-step organic synthesis, typically incorporated via N-alkylation, acylation, or coupling reactions to construct the target molecular scaffold |
| Pharmaceuticals | Structural modification unit in antipsychotic drug development | Introduces the cyclopentylpiperazine moiety during medicinal chemistry optimization to improve pharmacokinetic properties (e.g., blood-brain barrier penetration, metabolic stability) |
| Pharmaceuticals | Synthetic intermediate for JAK kinase inhibitor derivatives | Prepared by nucleophilic substitution or transition metal-catalyzed cross-coupling (e.g., Buchwald-Hartwig amination) with aryl halides to yield the target inhibitor |
Manufacturing Quality Control of 1-Amino-4-cyclopentylpiperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode-array detection; identification and quantification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generated electrochemically or added reagent to react stoichiometrically with water in the sample. |
| Heavy Metals (Total) | ICP-OES | Digestion followed by multi-element quantification via inductively coupled plasma optical emission spectrometry against calibrated metal standards. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an ion-exchange column with suppressed conductivity detection, referenced to chloride standard solutions. |
| Sulfate Impurity | Ion Chromatography | Anion-exchange separation and conductivity detection of sulfate, quantified relative to sulfate standard calibration. |
| Residual Catalyst (Pd) | ICP-MS | Acid digestion followed by ultra-trace palladium quantification using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using controlled heating and visual observation of phase change. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, used to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination using calibrated glass electrode in a saturated aqueous suspension or dilute solution at specified concentration and temperature. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to derive volume-based particle size distribution in a dispersed slurry. |
Technical Specifications of 1-Amino-4-cyclopentylpiperazine
| Test Item | Specification |
|---|---|
| Appearance | Colorless solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Amino-4-cyclopentylpiperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Amino-4-cyclopentylpiperazine
Safety Information of 1-Amino-4-cyclopentylpiperazine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-Amino-4-cyclopentylpiperazine
Industrial 1-Amino-4-cyclopentylpiperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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